Evidence map›Paper›PMID 32549252›Full record

ArticleMarine drugs2020

Characteristics, Cryoprotection Evaluation and In Vitro Release of BSA-Loaded Chitosan Nanoparticles.

Qinying Yan, Jiaqi Weng, Xieqi Wu, Weiwei Wang, Qingliang Yang, Fangyuan Guo, Danjun Wu, Ying Song, Fan Chen, Gensheng Yang

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Function ofInsects · 2026
    Article
  2. Article
  3. Article
  4. The role of nano-chelated iron on anatomical and biochemical characteristics and concentration of mineral nutrients in lettuce (Physiology and molecular biology of plants : an international journal of functional plant biology · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qinying YanCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.ORCID 0000-0003-0398-1505
Jiaqi WengCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.ORCID 0000-0002-2756-2682
Xieqi WuCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.
Weiwei WangCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.
Qingliang YangCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.ORCID 0000-0002-6905-8484
Fangyuan GuoCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.
Danjun WuCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.
Ying SongCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.
Fan ChenHubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Life Sciences School of Hubei University, 368 Youyi Road, Wuhan 430062, China.
Gensheng YangCollege of Pharmaceutical Sciences, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310032, China.ORCID 0000-0002-6127-7930
Zhejiang University of Technology · CNHubei University · CN

Funding

Natural Science Foundation of Zhejiang Province LY20H300005
6 · The paper itself

Abstract

Chitosan nanoparticles (CS-NPs) are under increasing investigation for the delivery of therapeutic proteins, such as vaccines, interferons, and biologics. A large number of studies have been taken on the characteristics of CS-NPs, and very few of these studies have focused on the microstructure of protein-loaded NPs. In this study, we prepared the CS-NPs by an ionic gelation method, and bovine serum albumin (BSA) was used as a model protein. Dynamic high pressure microfluidization (DHPM) was utilized to post-treat the nanoparticles so as to improve the uniformity, repeatability and controllability. The BSA-loaded NPs were then characterized for particle size,

Indexed as

Biological ProductsChitosanCold TemperatureCryoprotective AgentsDrug CarriersDrug CompoundingDrug LiberationDrug StabilityDrug StorageInterferonsNanoparticlesParticle SizeProtein StabilitySerum Albumin, BovineVaccinesBiological ProductsChitosanCryoprotective AgentsDrug CarriersInterferonsSerum Albumin, BovineVaccinescharacteristicschitosan nanoparticlescryoprotection evaluationdynamic high pressure microfluidization

Identifiers

PMID32549252
PMCPMC7345782
OpenAlexW3034688031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.