Evidence map›Paper›PMID 32549218›Full record

ArticleMolecules (Basel, Switzerland)2020

Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1

Haozhen Han, Chunpu Li, Man Li, Lisheng Yang, Sen Zhao, Zhifei Wang, Hong Liu, Dongxiang Liu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Epigenetic meets metabolism: novel vulnerabilities to fight cancer.Cell communication and signaling : CCS · 2023
    Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Haozhen HanDepartment of Pharmacology III, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Chunpu LiDepartment of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Man LiSchool of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Lisheng YangDepartment of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Sen ZhaoDepartment of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Zhifei WangSchool of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Hong LiuDepartment of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Dongxiang LiuDepartment of Pharmacology III, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Shanghai 201203, China.
Shanghai Institute of Materia Medica · CNShanghai University of Traditional Chinese Medicine · CNChinese Academy of Sciences · CNUniversity of Chinese Academy of Sciences · CN

Funding

National Natural Science Fund of China 21672233, 81973239, 81620108027, 21632008, 91229204, 81220108025 and 81602975
6 · The paper itself

Abstract

Sirtuins (SIRT1-7) are a family of NAD

Indexed as

Binding SitesDrug DesignHumansKineticsMolecular Docking SimulationMolecular StructureSirtuin 1Sirtuin 2Sirtuin 3SirtuinsStructure-Activity RelationshipTheophyllineSIRT1 protein, humanSIRT2 protein, humanSIRT3 protein, humanSIRT5 protein, humanSirtuin 1Sirtuin 2Sirtuin 3SirtuinsTheophyllinedeacetylaseinhibitorsirtuinsstructure–activity relationship

Identifiers

PMID32549218
PMCPMC7356367
OpenAlexW3035571194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.