Evidence map›Paper›PMID 32548923›Full record

ArticleAnnals of clinical and translational neurology2020

Effect of thalamic deep brain stimulation on swallowing in patients with essential tremor.

Sriramya Lapa, Inga Claus, Sarah C Reitz, Johanna Quick-Weller, Sonja Sauer, Sigrid Colbow, Christiane Nasari, Rainer Dziewas, Jun-Suk Kang, Simon Baudrexel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
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  8. Comparing Programming Sessions of Vim-DBS.Frontiers in neurology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sriramya LapaDepartment of Neurology, University Hospital Frankfurt, Frankfurt, Germany.ORCID 0000-0001-9726-8385
Inga ClausDepartment of Neurology, University Hospital Muenster, Muenster, Germany.
Sarah C ReitzDepartment of Neurology, University Hospital Frankfurt, Frankfurt, Germany.
Johanna Quick-WellerDepartment of Neurosurgery, University Hospital Frankfurt, Frankfurt, Germany.
Sonja SauerDepartment of Neurology, University Hospital Muenster, Muenster, Germany.
Sigrid ColbowDepartment of Neurology, University Hospital Muenster, Muenster, Germany.
Christiane NasariDepartment of Neurology, University Hospital Frankfurt, Frankfurt, Germany.
Rainer DziewasDepartment of Neurology, University Hospital Muenster, Muenster, Germany.
Jun-Suk KangDepartment of Neurology, University Hospital Frankfurt, Frankfurt, Germany.
Simon BaudrexelDepartment of Neurology, University Hospital Frankfurt, Frankfurt, Germany.
Tobias WarneckeDepartment of Neurology, University Hospital Muenster, Muenster, Germany.
Goethe University Frankfurt · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDeep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) is a mainstay treatment for severe and drug-refractory essential tremor (ET). Although stimulation-induced dysarthria has been extensively described, possible impairment of swallowing has not been systematically investigated yet.

methodsTwelve patients with ET and bilateral VIM-DBS with self-reported dysphagia after VIM-DBS were included. Swallowing function was assessed clinically and using by flexible endoscopic evaluation of swallowing in the stim-ON and in the stim-OFF condition. Presence, severity, and improvement of dysphagia were recorded.

resultsDuring stim-ON, the presence of dysphagia could be objectified in all patients, 42% showing mild, 42% moderate, and 16 % severe dysphagia. During stim-OFF, all patients experienced a statistically significant improvement of swallowing function.

interpretationVIM-DBS may have an impact on swallowing physiology in ET-patients. Further studies to elucidate the prevalence and underlying pathophysiological mechanisms are warranted.

Indexed as

Ventral Thalamic NucleiAgedAged, 80 and overDeep Brain StimulationDeglutition DisordersEssential TremorFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness Index

Identifiers

PMID32548923
PMCPMC7359107
OpenAlexW3034208765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.