Evidence map›Paper›PMID 32548811›Full record

ArticleDigestive diseases and sciences2021

Albumin-Bilirubin (ALBI) Grade-Based Nomogram for Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization.

Shu-Yein Ho, Chia-Yang Hsu, Po-Hong Liu, Rheun-Chuan Lee, Chih-Chieh Ko, Yi-Hsiang Huang, Chien-Wei Su, Ming-Chih Hou, Teh-Ia Huo

Abstract readValidation Study
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In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Albumin-bilirubin grade and sarcopenia as predictors of prognosis in patients with unresectable intermediate and advanced-stage hepatocellular carcinoma.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Article
  3. Impact of Child Pugh B Stage for the Treatment of Advanced HCC.Journal of hepatocellular carcinoma · 2026
    Review
  4. Article
  5. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Shu-Yein HoDepartment of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chia-Yang HsuFaculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Po-Hong LiuFaculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Rheun-Chuan LeeDepartment of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chih-Chieh KoDepartment of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Yi-Hsiang HuangDepartment of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chien-Wei Su *Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Ming-Chih HouDepartment of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Teh-Ia HuoDepartment of Medical Research, Taipei Veterans General Hospital, No. 201, Sec. 2, Shipai Rd., Taipei, 11217, Taiwan. tihuo@vghtpe.gov.tw.ORCID 0000-0003-2202-521X
National Yang Ming Chiao Tung University · TW

Funding

Taipei Veterans General Hospital V107A-008Taipei Veterans General Hospital V108A-002Taipei Veterans General Hospital VN107-04Taipei Veterans General Hospital VN108-05
6 · The paper itself

Abstract

BACKGROUND/

aimThe prognosis of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE) is highly heterogeneous because of variable characteristics of tumor burden and liver dysfunction. We aimed to propose and validate an albumin-bilirubin (ALBI) grade-based prognostic nomogram for HCC patients undergoing TACE.

methodsA total of 1051 patients with HCC undergoing TACE were randomly assigned to derivation (n = 525) and validation (n = 526) set in this retrospective study based on prospective data. The multivariate Cox proportional hazards model in derivation set was used to generate the nomogram. The predictive accuracy of the nomogram was evaluated by discrimination and calibration tests.

resultsIn multivariate analysis, presence of ascites, ALBI grade 2-3, serum ɑ-fetoprotein level ≥ 400 ng/mL, total tumor volume ≥ 396 cm

conclusionsThe ALBI grade-based prognostic model can well discriminate the survival in HCC patients undergoing TACE. The proposed easy-to-use nomogram may accurately predict the survival at 3 and 5 years for individual HCC patient in the precision medicine era.

Indexed as

Chemoembolization, TherapeuticDecision Support TechniquesNomogramsAgedAged, 80 and overBilirubinCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMaleMiddle AgedNeoplasm StagingPredictive Value of TestsReproducibility of ResultsRetrospective StudiesALB protein, humanBilirubinSerum Albumin, HumanHepatocellular carcinomaNomogramTransarterial chemoembolization

Identifiers

PMID32548811
OpenAlexW3034759381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.