Evidence map›Paper›PMID 32548771›Full record

ArticleInsights into imaging2020

Fast acquisition abdominal MRI study for the investigation of suspected acute appendicitis in paediatric patients.

Karl James, Patrick Duffy, Richard G Kavanagh, Brian W Carey, Stephen Power, David Ryan, Stella Joyce, Aoife Feeley, Peter Murphy, Emmet Andrews and 5 more

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis.The Cochrane database of systematic reviews · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Karl JamesDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Patrick DuffyDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Richard G KavanaghDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Brian W CareyDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Stephen PowerDepartment of Radiology, Cork University Hospital, Cork, Ireland.
David RyanDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Stella JoyceDepartment of Radiology, University College Cork, Cork, Ireland.
Aoife FeeleySchool of Medicine, University College Cork, Cork, Ireland.
Peter MurphyPET/CT-MRI Unit, Cork University Hospital, Cork, Ireland.
Emmet AndrewsDepartment of Surgery, Cork University Hospital, Cork, Ireland.
Mark F McEnteeDepartment of Radiography, University College Cork, Cork, Ireland.
Michael MooreDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Conor BogueDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Michael M MaherDepartment of Radiology, Cork University Hospital, Cork, Ireland.
Owen J O' ConnorDepartment of Radiology, Cork University Hospital, Cork, Ireland. oj.oconnor@ucc.ie.ORCID http://orcid.org/0000-0002-0276-1335
Cork University Hospital · IEUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the diagnostic accuracy of fast acquisition MRI in suspected cases of paediatric appendicitis presenting to a tertiary referral hospital. MATERIALS AND

methodsA prospective study was undertaken between May and October 2017 of 52 children who presented with suspected appendicitis and were referred for an abdominal ultrasound. All patients included in this study received both an abdominal ultrasound and five-sequence MRI consisting of axial and coronal gradient echo T2 scans, fat-saturated SSFSE and a diffusion-weighted scan. Participants were randomised into groups of MRI with breath-holds or MRI with free breathing. A patient satisfaction survey was also carried out. Histopathology findings, where available, were used as a gold standard for the purposes of data analysis. Statistical analysis was performed, and p values < 0.05 were considered statistically significant.

resultsUltrasound had a sensitivity and specificity of 25% and 92.9%, respectively. MRI with breath-hold had a sensitivity and specificity of 81.8% and 66.7%, respectively, whilst MRI with free breathing was superior with sensitivity and specificity of 92.3% and 84.2%, respectively. MRI with free breathing was also more time efficient (p < 0.0001). Group statistics were comparable (p < 0.05).

conclusionsThe use of fast acquisition MRI protocols, particularly free breathing sequences, for patients admitted with suspected appendicitis can result in faster diagnosis, treatment and discharge. It also has a statistically significant diagnostic advantage over ultrasound. Additionally, the higher specificity of MR can reduce the number of negative appendectomies performed in tertiary centres.

Indexed as

Acute appendicitisMagnetic resonance imagingPaediatricUltrasound

Identifiers

PMID32548771
PMCPMC7297877
OpenAlexW3034656104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.