Evidence map›Paper›PMID 32548699›Full record

ArticleDiabetologia2020

Live-born children after assisted reproduction in women with type 1 diabetes and type 2 diabetes: a nationwide cohort study.

Michael Due Larsen, Dorte Møller Jensen, Jens Fedder, Line Riis Jølving, Bente Mertz Nørgård

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Michael Due LarsenDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Erling Skjalgssons gt. 1, Laboratoriesenteret, 5. etasje, 7491, Trondheim, Norway. michael.d.larsen@ntnu.no.ORCID 0000-0002-0623-2481
Dorte Møller JensenSteno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-3298-9824
Jens FedderDepartment D, Centre of Andrology and Fertility Clinic, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-5383-5501
Line Riis JølvingCenter for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-7433-7656
Bente Mertz NørgårdCenter for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-9514-3033
University of Southern Denmark · DKNorwegian University of Science and Technology · NOSteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisType 1 and type 2 diabetes are among the most prevalent chronic diseases in women in the fertile years and women with diabetes may experience several reproductive issues. We aimed to examine the chance of biochemical pregnancy, clinical pregnancy and live birth after assisted reproductive technology (ART) treatment in women with type 1 and type 2 diabetes and whether obesity per se influenced the results.

methodsThis nationwide register-based cohort study is based on the Danish ART Registry comprising 594 women with either type 1 diabetes or type 2 diabetes from 2006 to 2017.

resultsRelative to women without diabetes, the adjusted OR (95% CI) of a live birth per embryo transfer was 0.50 (0.36, 0.71) in women with type 2 diabetes and 1.10 (0.86, 1.41) in women with type 1 diabetes. CONCLUSIONS/

interpretationOur data on the efficacy of ART treatment in women with type 1 and type 2 diabetes is the first in this field. When compared with women without diabetes, women with type 1 diabetes had an equivalent chance of a live birth per embryo transfer whereas women with type 2 diabetes had a reduced chance. The findings in women with type 2 diabetes did not seem to be driven by obesity per se as the same pattern was seen in both normal-weight and obese women. Graphical abstract.

Indexed as

Fertilization in VitroLive BirthPregnancy in DiabeticsAdultDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Embryo TransferFemaleHumansInfertilityPregnancyPregnancy RateReproductive Techniques, AssistedSperm Injections, IntracytoplasmicTreatment OutcomeAssisted reproductive technologyBody mass indexCohort studyDenmarkEmbryo transferEpidemiologyInfertilityIn vitro fertilisationType 1 diabetesType 2 diabetes

Identifiers

PMID32548699
PMCPMC7406522
OpenAlexW3035279777

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.