ArticleACS omega2020
Development of a Simple, Fast, and Cost-Effective Nanobased Immunoassay Method for Detecting Norovirus in Food Samples.
Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Conventional and advanced detection techniques of foodborne pathogens: A comprehensive review.Heliyon · 2023Article
- Recent advances in airborne pathogen detection using optical and electrochemical biosensors.Analytica chimica acta · 2022Review
- Recent Advances in Early Diagnosis of Viruses Associated with Gastroenteritis by Biosensors.Biosensors · 2022Review
- Article
- Magnetic-Core/Gold-Shell Nanoparticles for the Detection of Hydrophobic Chemical Contaminants.Nanomaterials (Basel, Switzerland) · 2022Article
- Real-time, selective, and low-cost detection of trace level SARS-CoV-2 spike-protein for cold-chain food quarantine.NPJ science of food · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents a quick, low-cost, and easy technique for the detection of norovirus in several food samples, including cucumber, lettuce, and chicken. The developed sandwich immunoassay method depends on employing nanotechnology for the detection step. Lactoferrin immobilized on activated Q-tips cotton swabs was used as a general capturing reagent to bind viruses from the sample surface. The cotton swabs were then submerged in a gold nanoparticle solution, which had previously decorated with a specific antibody for noroviruses. Positive samples retained the red color of the gold nanoparticles on the surface of Q-tips, even after washing, while the negative control samples easily lost their color through washing. The results confirmed that the developed assay has superior sensitivity and selectivity with a LOD between 10 and 53 pfu/mL for all tested samples. In light of the difficulty, complexity, and high cost of the methods recently used for detecting viruses in food samples, this method presents a promising reliable technique that can be employed for the rapid detection of norovirus in food samples with an acceptable accuracy.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.