Evidence map›Paper›PMID 32548384›Full record

ArticleACS omega2020

Paper-Based Platform with an In Situ Molecularly Imprinted Polymer for β-Amyloid.

Marta V Pereira, Ana C Marques, Daniela Oliveira, Rodrigo Martins, Felismina T C Moreira, M Goreti F Sales, Elvira Fortunato

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marta V PereiraBioMark, Sensor Research/ISEP, School of Engineering, Polytechnic Institute Porto 4249-015 Porto, Portugal.
Ana C MarquesBioMark, Sensor Research/ISEP, School of Engineering, Polytechnic Institute Porto 4249-015 Porto, Portugal.
Daniela OliveiraBioMark, Sensor Research/ISEP, School of Engineering, Polytechnic Institute Porto 4249-015 Porto, Portugal.
Rodrigo Martinsi3N/CENIMAT, Department of Materials Science, Faculty of Science and Technology, Universidade NOVA de Lisboa and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.
Felismina T C MoreiraBioMark, Sensor Research/ISEP, School of Engineering, Polytechnic Institute Porto 4249-015 Porto, Portugal.
M Goreti F SalesBioMark, Sensor Research/ISEP, School of Engineering, Polytechnic Institute Porto 4249-015 Porto, Portugal.
Elvira Fortunatoi3N/CENIMAT, Department of Materials Science, Faculty of Science and Technology, Universidade NOVA de Lisboa and CEMOP/UNINOVA, Campus de Caparica, 2829-516 Caparica, Portugal.
Universidade Nova de Lisboa · PTPolytechnic Institute of Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is one of the most common forms of dementia affecting millions of people worldwide. Currently, an easy and effective form of diagnosis is missing, which significantly hinders a possible improvement of the patient's quality of life. In this context, biosensors emerge as a future solution, opening the doors for preventive medicine and allowing the premature diagnosis of numerous pathologies. This work presents a pioneering biosensor that combines a bottom-up design approach using paper as a platform for the electrochemical recognition of peptide amyloid β-42 (Aβ-42), a biomarker for AD present in blood, associated with visible differences in the brain tissue and responsible for the formation of senile plaques. The sensor layer relies on a molecularly imprinted polymer as a biorecognition element, created on the carbon ink electrode's surface by electropolymerizing a mixture of the target analyte (Aβ-42) and a monomer (

Identifiers

PMID32548384
PMCPMC7271027
OpenAlexW3025147002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.