Evidence map›Paper›PMID 32548331›Full record

ArticleHeliyon2020

Age and gender-specific antibiotic resistance patterns among Bangladeshi patients with urinary tract infection caused by

Ahmed Hossain, Saeem Arafat Hossain, Aneeka Nawar Fatema, Abrar Wahab, Mohammad Morshad Alam, Md Nazrul Islam, Mohammad Zakir Hossain, Gias U Ahsan

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  7. Detection ofHeliyon · 2024
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  8. Investigating trends in antibiotic resistance ofMicrobiology (Reading, England) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ahmed HossainDepartment of Public Health, North South University, Dhaka, 1229, Bangladesh.
Saeem Arafat HossainDepartment of Public Health, North South University, Dhaka, 1229, Bangladesh.
Aneeka Nawar FatemaCenter for Climate Change and Environmental Research, BRAC University, Dhaka, Bangladesh.
Abrar WahabDepartment of Public Health, North South University, Dhaka, 1229, Bangladesh.
Mohammad Morshad AlamDepartment of Public Health, North South University, Dhaka, 1229, Bangladesh.
Md Nazrul IslamMedinova Medical Services Ltd., Dhaka, Bangladesh.
Mohammad Zakir HossainNational Institute of Ophthalmology, Dhaka, Bangladesh.
Gias U AhsanDepartment of Public Health, North South University, Dhaka, 1229, Bangladesh.
North South University · BDBRAC University · BDNova Medical (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Bangladesh, treatment for urinary tract infection has become increasingly difficult due to antibiotic resistance. In addition, the prescription of age and gender-specific drugs is still far from being practiced in Bangladesh. We are examining trends of antibiotic resistance per age and gender in patients with urinary tract infection (UTI) caused by the most frequent agent,

methodsWe determined the resistance of 1663

resultsImipenem with 1.9% resistance of all isolates found to be the lowest percentage of resistance. Meropenem (2.8%), amikacin (2.8%), colistin (2.9%), and nitrofurantoin (15.8%) showed low resistance percentages. The sensitivity analysis suggests that age and gender (area under curve = 0.67) should be taken into consideration to prescribe amikacin. The increasing odds ratios (OR) by age groups suggest that amikacin is a less effective agent for older patients with UTIs. Moreover, nitrofurantoin (OR = 1.45, 95% confidence interval (CI) = 1.07-1.95) and colistin (OR = 2.09, CI = 1.13-3.76) were less effective against isolates obtained from males compared to isolates obtained from females. Meropenem was effective against bacteria obtained from all age groups and genders. On the other hand, efficacy of imipenem was lower in isolates obtained from adults older than 40 years (OR: 0.44 for < = 18 years, OR = 0.47 for 19-40 years, OR = 0.86 for 41-60 years; reference: > = 61 years).

conclusionIn Bangladesh, meropenem, imipenem, amikacin, colistin, and nitrofurantoin are suitable therapeutic alternatives against urinary tract pathogens. Among the oral agents, amikacin, colistin, and nitrofurantoin should be prescribed, taking consideration of age and gender. These results will assist physicians in prescribing effective primary care antibiotics for UTI patients and encouraging the implementation of health policies for a safe prescription of antibiotics.

Indexed as

Antibiotic resistanceBangladeshClinical researchDiagnosticsEscherichia coliInfectious diseasePrimary health carePublic healthUrinary tract infectionUrology

Identifiers

PMID32548331
PMCPMC7286969
OpenAlexW3035308608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.