Evidence map›Paper›PMID 32548177›Full record

ArticleMicrobial cell (Graz, Austria)2020

Broad-spectrum antifungal activities and mechanism of drimane sesquiterpenoids.

Edruce Edouarzin, Connor Horn, Anuja Paudyal, Cunli Zhang, Jianyu Lu, Zongbo Tong, Guri Giaever, Corey Nislow, Raja Veerapandian, Duy H Hua and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Chemical characterization and biological activity of Curvularia Lunata, an endophytic fungus isolated from lemongrass (Cymbopogon citratus).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Molecules (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Anticapsular and Antifungal Activity of α-Cyperone.Antibiotics (Basel, Switzerland) · 2021
    Article
  15. Fungal infections in humans: the silent crisis.Microbial cell (Graz, Austria) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Edruce EdouarzinDepartment of Chemistry, 1212 Mid Campus Drive North, Kansas State University, Manhattan, KS 66506 USA.
Connor HornDivision of Biology, 1717 Claflin Road, Kansas State University, Manhattan, KS 66506 USA.
Anuja PaudyalDivision of Biology, 1717 Claflin Road, Kansas State University, Manhattan, KS 66506 USA.
Cunli ZhangDepartment of Chemistry, 1212 Mid Campus Drive North, Kansas State University, Manhattan, KS 66506 USA.
Jianyu LuDepartment of Chemistry, 1212 Mid Campus Drive North, Kansas State University, Manhattan, KS 66506 USA.
Zongbo TongDepartment of Chemistry, 1212 Mid Campus Drive North, Kansas State University, Manhattan, KS 66506 USA.
Guri GiaeverFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC Canada V6T 1Z3.
Corey NislowFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC Canada V6T 1Z3.
Raja VeerapandianDivision of Biology, 1717 Claflin Road, Kansas State University, Manhattan, KS 66506 USA.
Duy H HuaDepartment of Chemistry, 1212 Mid Campus Drive North, Kansas State University, Manhattan, KS 66506 USA.
Govindsamy VediyappanDivision of Biology, 1717 Claflin Road, Kansas State University, Manhattan, KS 66506 USA.
University of British Columbia · CA

Funding

Catalytic Asymmetric Oxidation of Alkenes and AlkanesR01GM128659 · NIGMS · KANSAS STATE UNIVERSITY · PI HUA, DUY H · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM128659
6 · The paper itself

Abstract

Eight drimane sesquiterpenoids including (-)-drimenol and (+)-albicanol were synthesized from (+)-sclareolide and evaluated for their antifungal activities. Three compounds, (-)-drimenol, (+)-albicanol, and (1

Indexed as

Candida albicansCandida aurisCrk1 kinase associateddrimenolfungicidal antifungalnovel mechanism of actionSaccharomyces cerevisiaesynthesis

Identifiers

PMID32548177
PMCPMC7278516
OpenAlexW3029596757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.