Evidence map›Paper›PMID 32548101›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos.

Seema Gupta, Indu Singh, Ashwani K Sharma, Pradeep Kumar

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Current protein & peptide science · 2025
    Article
  9. Review
  10. Article
  11. Peptide Self-Assembled Nanocarriers for Cancer Drug Delivery.The journal of physical chemistry. B · 2023
    Review
  12. Article
  13. Review
  14. Enhancing Photothermal Therapy Efficacy byACS applied materials & interfaces · 2023
    Review
  15. Anion Effects on the Supramolecular Self-Assembly of Cationic Phenylalanine Derivatives.Langmuir : the ACS journal of surfaces and colloids · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seema GuptaChemistry Department, Acharya Narendra Dev College, University of Delhi, New Delhi, India.
Indu SinghChemistry Department, Acharya Narendra Dev College, University of Delhi, New Delhi, India.
Ashwani K SharmaNucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Pradeep KumarNucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The translational therapies to promote interaction between cell and signal come with stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet blessed with robust intermolecular association, the peptides, are privileged to make the cut-off for sensing the cell-signal for biologics delivery and tissue engineering. The signature service and insoluble network formation of the peptide self-assemblies as hydrogels have drawn a spell of research activity among the scientists all around the globe in the past decades. The therapeutic peptide market players are anticipating promising growth opportunities due to the ample technological advancements in this field. The presence of the other organic moieties, enzyme substrates and well-established protecting groups like Fmoc and Boc etc., bring the best of both worlds. Since the large sequences of peptides severely limit the purification and their isolation, this article reviews the account of last 5 years' efforts on novel approaches for formulation and development of single molecule amino acids, ultra-short peptide self-assemblies (di- and tri- peptides only) and their derivatives as drug/gene carriers and tissue-engineering systems.

Indexed as

amphiphilicitydrug deliverypeptideself-assemblytissue engineering

Identifiers

PMID32548101
PMCPMC7273840

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.