Evidence map›Paper›PMID 32548084›Full record

ReviewFrontiers in pediatrics2020

A Review on Non-invasive Respiratory Support for Management of Respiratory Distress in Extremely Preterm Infants.

Yuan Shi, Hemananda Muniraman, Manoj Biniwale, Rangasamy Ramanathan

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05081973 unknown statusnot on this mapstarted 2021, after this paper: background citation

A Model for Predicting Extubation Success Based on the "Extubation Readiness Estimator" and Lung Ultrasonography Score in Premature Babies

TypeobservationalSponsorMarmara UniversityRan2021 to 2024Enrolled114ConditionsNeonatal Respiratory Failure, Invasive Mechanical Ventilation, Extubation FailureArmsA model for predicting extubation success based on extubation readiness estimator and lung ultrasonography score
NCT06620107 nacompletednot on this mapstarted 2023, after this paper: background citation

Noninvasive High Frequency Oscillation Ventilation (NHFOV) in Comparison to Noninvasive Intermittent Positive Pressure Ventilation (NIPPV) As Post-extubation Support in Preterm Neonates

TypeinterventionalSponsorKafrelsheikh UniversityRan2023 to 2024Enrolled80ConditionsNoninvasive VentilationArmsnoninvasive high frequency oscillation ventilation, noninvasive positive pressure ventilation
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Feasibility of lung ultrasound-guided positive end-expiratory pressure adjustment in newborns.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Article
  7. Article
  8. Bubble NIPPV: Guidelines for Use.Children (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Management of neonates with respiratory distress syndrome in resource-limited settings.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Yuan ShiMinistry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing, China.
Hemananda MuniramanDepartment of Pediatrics, Creighton School of Medicine, Omaha, NE, United States.
Manoj BiniwaleNeonatology Association Limited, Obstetrix Medical Group of Phoenix, Mednax, Arizona, AZ, United States.
Rangasamy RamanathanDivision of Neonatology, LAC+USC Medical Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Children's Hospital of Chongqing Medical University · CNCreighton University · USMednax (United States) · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Majority of extremely preterm infants require positive pressure ventilatory support at the time of delivery or during the transitional period. Most of these infants present with respiratory distress (RD) and continue to require significant respiratory support in the neonatal intensive care unit (NICU). Bronchopulmonary dysplasia (BPD) remains as one of the major morbidities among survivors of the extremely preterm infants. BPD is associated with long-term adverse pulmonary and neurological outcomes. Invasive mechanical ventilation (IMV) and supplemental oxygen are two major risk factors for the development of BPD. Non-invasive ventilation (NIV) has been shown to decrease the need for IMV and reduce the risk of BPD when compared to IMV. This article reviews respiratory management with current NIV support strategies in extremely preterm infants both in delivery room as well as in the NICU and discusses the evidence to support commonly used NIV modes including nasal continuous positive airway pressure (NCPAP), nasal intermittent positive pressure ventilation (NIPPV), bi-level positive pressure (BI-PAP), high flow nasal cannula (HFNC), and newer NIV strategies currently being studied including, nasal high frequency ventilation (NHFV) and non-invasive neutrally adjusted ventilatory assist (NIV-NAVA). Randomized, clinical trials have shown that early NIPPV is superior to NCPAP to decrease the need for intubation and IMV in preterm infants with RD. It is also important to understand that selection of the device used to deliver NIPPV has a significant impact on its success. Ventilator generated NIPPV results in significantly lower rates of extubation failures when compared to Bi-PAP. Future studies should address synchronized NIPPV including NIV-NAVA and early rescue use of NHFV in the respiratory management of extremely preterm infants.

Indexed as

bronchopulmonary dysplasia (BPD)high flow nasal cannula (HFNC)nasal continuous positive airway pressure (NCPAP)nasal high frequency ventilation (NHFV)nasal intermittent positive pressure ventilation (NIPPV)noninvasive ventilation-neurally adjusted ventilatory assist (NIVNAVA)noninvasive ventilation (NIV)

Identifiers

PMID32548084
PMCPMC7270199
OpenAlexW3026977312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.