Evidence map›Paper›PMID 32548071›Full record

ArticleJournal of diabetes and metabolic disorders2020

A genetic approach to study the relationship between maternal Vitamin D status and newborn anthropometry measurements: the Vitamin D pregnant mother (VDPM) cohort study.

Arif Sabta Aji, Erwinda Erwinda, Rosfita Rasyid, Yusrawati Yusrawati, Safarina G Malik, Buthaina Alathari, Julie Anne Lovegrove, Nur Indrawaty Lipoeto, Karani Santhanakrishnan Vimaleswaran

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Arif Sabta AjiDepartment of Biomedical Science, Faculty of Medicine, Andalas University, Padang, 25127 Indonesia.
Erwinda ErwindaDepartment of Public Health, Faculty of Medicine, Andalas University, Padang, West Sumatra 25127 Indonesia.
Rosfita RasyidDepartment of Public Health, Faculty of Medicine, Andalas University, Padang, West Sumatra 25127 Indonesia.
Yusrawati YusrawatiDepartment of Obstetrics and Gynecology, Faculty of Medicine, Andalas University, Padang, 25127 Indonesia.
Safarina G MalikEijkman Institute for Molecular Biology, Jakarta, 10430 Indonesia.
Buthaina AlathariHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK.
Julie Anne LovegroveHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK.
Nur Indrawaty LipoetoDepartment of Nutrition, Faculty of Medicine, Andalas University, Padang, 25127 Indonesia.
Karani Santhanakrishnan VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK.
Andalas University · IDUniversity of Reading · GBEijkman Institute for Molecular Biology · IDUniversitas Teknologi Yogyakarta · ID

Funding

Medical Research Council MR/S024778/1
6 · The paper itself

Abstract

purposeAdverse effects of maternal vitamin D deficiency have been linked to adverse pregnancy outcomes. We investigated the relationship between maternal vitamin D status and newborn anthropometry measurements using a genetic approach and examined the interaction between genetic variations in involved in vitamin D synthesis and metabolism and maternal vitamin D concentrations on newborn anthropometry.

methodsThe study was conducted in 183 pregnant Indonesian Minangkabau women. Genetic risk scores (GRSs) were created using six vitamin D-related single nucleotide polymorphisms and their association with 25-hydroxyvitamin D [25(OH)D] levels and newborn anthropometry (183 infants) were investigated.

resultsThere was no significant association between maternal 25(OH)D concentrations and newborn anthropometry measurements (

conclusionOur findings demonstrate the impact of vitamin D-related GRS on 25(OH)D and provides evidence for the effect of vitamin D-related GRS on newborn anthropometry through the influence of serum 25(OH)D levels among Indonesian pregnant women. Even though our study is a prospective cohort, before the implementation of vitamin D supplementation programs in Indonesia to prevent adverse pregnancy outcomes, further large studies are required to confirm our findings.

Indexed as

25-hydroxyvitamin DGenetic risk score, West SumatraNewborn anthropometryPregnancySingle nucleotide polymorphismsVitamin D

Identifiers

PMID32548071
PMCPMC7270445
OpenAlexW3003583701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.