Evidence map›Paper›PMID 32547872›Full record

ArticlePeerJ2020

Nebulized dexmedetomidine improves pulmonary shunt and lung mechanics during one-lung ventilation: a randomized clinical controlled trial.

Bo Xu, Hong Gao, Dan Li, Chunxiao Hu, Jianping Yang

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04932746 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect of Dexmedetomidine on Oxygen and Intrapulmonary Shunt During One Lung Ventilation in Pediatric Surgery: Randomized Controlled Trial

TypeinterventionalSponsorDamascus UniversityRan2021 to 2023Enrolled110ConditionsOne Lung Ventilation OLV, Esophageal Atresia, Hydrocystoma, PneumonectomyArmsDexmedetomidine, Placebo
NCT06207331 naterminatednot on this mapstarted 2023, after this paper: background citation

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorThe Second Affiliated Hospital of Chongqing Medical UniversityRan2023 to 2024Enrolled6ConditionsRespiratory Function Tests, Chronic Obstructive Pulmonary Disease, DexmedetomidineArmsDexmedetomidine 0.5 μg/kg, Dexmedetomidine 1 μg/kg, Saline
NCT06505772 nacompletednot on this mapstarted 2023, after this paper: background citation

Dexmedetomidine Improves Oxygenation and Reduces Pulmonary Shunt in High-Risk Pediatric Patients Undergoing One-Lung Ventilation for Thoracic Surgery: A Double-Blind Randomized Controlled Trial at Damascus University Children's Hospital

TypeinterventionalSponsorDamascus UniversityRan2023 to 2024Enrolled78ConditionsOne-Lung Ventilation, Thoracic SurgeryArmsDexmedetomidine, Normal saline
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bo XuThe Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Hong GaoThe Department of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University Wuxi, Jiangsu, China.
Dan LiThe Department of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University Wuxi, Jiangsu, China.
Chunxiao HuThe Department of Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University Wuxi, Jiangsu, China.
Jianping YangThe Department of Anesthesiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Nanjing Medical University · CNFirst Affiliated Hospital of Soochow University · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDexmedetomidine (Dex), a selective a

methodsOne hundred and twenty-eight patients undergoing elective thoracoscopic surgery were included in this study and randomly divided into four groups: 0.9% saline (Placebo group), 0.5 µg/kg (Dex

resultsDex decreased the requirement of propofol in a dose-dependent manner(

Indexed as

AnesthesiaArterial oxygenationDexmedetomidineHypoxic pulmonary vasoconstrictionIntrapulmonary shuntLung mechanicsNebulizerOne-lung ventilationThoracic surgery

Identifiers

PMID32547872
PMCPMC7278887
OpenAlexW3032990196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.