Evidence map›Paper›PMID 32547680›Full record

ReviewWorld journal of stem cells2020

Molecular modulation of autophagy: New venture to target resistant cancer stem cells.

Harpreet K Mandhair, Miroslav Arambasic, Urban Novak, Ramin Radpour

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of stem cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. The therapeutic potential of RNA m(6)A in lung cancer.Cell communication and signaling : CCS · 2024
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  3. Targeting Lipid Metabolism in Cancer Stem Cells for Anticancer Treatment.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Harpreet K MandhairDepartment for BioMedical Research, University of Bern, Bern 3008, Switzerland.
Miroslav ArambasicDepartment for BioMedical Research, University of Bern, Bern 3008, Switzerland.
Urban NovakDepartment for BioMedical Research, University of Bern, Bern 3008, Switzerland.
Ramin RadpourDepartment for BioMedical Research, University of Bern, Bern 3008, Switzerland.
University of Bern · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a highly regulated catabolic process in which superfluous, damaged organelles and other cytoplasmic constituents are delivered to the lysosome for clearance and the generation of macromolecule substrates during basal or stressed conditions. Autophagy is a bimodal process with a context dependent role in the initiation and the development of cancers. For instance, autophagy provides an adaptive response to cancer stem cells to survive metabolic stresses, by influencing disease propagation

Indexed as

AutophagyCancer cellsCancer metastasisCancer stem cellsCancer therapyTherapeutic resistance

Identifiers

PMID32547680
PMCPMC7280868
OpenAlexW3028848257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.