ArticleThyroid research2020
Elevated serum TSH concentrations are associated with higher BMI Z-scores in southern Iranian children and adolescents.
Article in Thyroid research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Serum Copper/Zinc Ratio in Overweight and Obese Children: a Cross-Sectional Study.Biological trace element research · 2024Article
- Exploring the oral-gut microbiota during thyroid cancer: Factors affecting the thyroid functions and cancer development.Food science & nutrition · 2023Review
- Impact of Weight Reduction on Thyroid Function and Nonalcoholic Fatty Liver among Egyptian Adolescents with Obesity.International journal of endocrinology · 2022Article
- Leptin Does Not Influence TSH Levels in Obese Short Children.Frontiers in endocrinology · 2022Article
- Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels.International journal of molecular sciences · 2021Review
- Transient Hyperthyrotropinemia in Outpatient Children with Acute Infections of the Respiratory System.International journal of environmental research and public health · 2021Article
- Considerations in evaluating the thyroid gland in a primary care setting.Journal of family medicine and primary care · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical hypothyroidism is defined as elevated TSH levels while T4 or FT4 levels are normal. Elevated TSH levels are linked with obesity in adults. In a recent meta-analysis in Iran, 6.1% of children below 18 had obesity. Due to the low number of studies on the subject in children we, designed the study to assess the relation between BMI Z-score and TSH levels in children and adolescence.
methodThis cross-sectional study was performed in a pediatric endocrinology clinic in Shiraz. Children aged between 2 to 18 years that came to the clinic for routine growth assessment follow up from January till April 2018 were considered. 850 children including 365 boys and 485 girls were included.
resultsPrevalence of subclinical hypothyroidism is increased in higher BMI groups. 9.9, 13.8, 17.2 and 20.5% of underweight, healthy weight, overweight and obese had subclinical hypothyroidism respectively. Obese and overweight participants had higher odds of subclinical hypothyroidism than those who were not (OR:1.649,
conclusionBMI Z-score and elevated TSH levels are positively correlated however studies should be performed on establishing the causality.
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