Evidence map›Paper›PMID 32547591›Full record

ArticleFrontiers in plant science2020

Summary of Discussions From the 2019 OECD Conference on RNAi Based Pesticides.

Michael L Mendelsohn, Achim Gathmann, Dimitra Kardassi, Magdalini Sachana, Emily M Hopwood, Antje Dietz-Pfeilstetter, Stephani Michelsen-Correa, Stephen J Fletcher, András Székács

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024
    Review
  5. Review
  6. Characterization of Ionotropic Receptor GenePlants (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Comparison of Antifungal Activity ofPlants (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 7 countries.

Michael L MendelsohnBiopesticides and Pollution Prevention Division, Office of Pesticide Programs, United States Environmental Protection Agency, Washington, DC, United States.
Achim GathmannFederal Office of Consumer Protection and Food Safety, Department of Plant Protection Products, Unit Environment, Braunschweig, Germany.
Dimitra KardassiPesticide Peer Review Unit, Scientific Evaluation of Regulated Products Directorate, European Food Safety Agency, Parma, Italy.
Magdalini SachanaEnvironment Health and Safety Division, Environment Directorate, Organisation for Economic Cooperation and Development, Paris, France.
Emily M HopwoodHealth Evaluation Directorate, Pest Management Regulatory Agency, Health Canada, Ottawa, ON, Canada.
Antje Dietz-PfeilstetterInstitute for Biosafety in Plant Biotechnology, Julius Kühn-Institut, Federal Research Centre for Cultivated Plants, Braunschweig, Germany.
Stephani Michelsen-CorreaScience and Technology Policy Fellow, American Association for the Advancement of Science, Washington, DC, United States.
Stephen J FletcherCentre for Horticultural Science, Queensland Alliance for Agriculture and Food Innovation, University of Queensland, St. Lucia, QLD, Australia.
András SzékácsAgro-Environmental Research Institute, National Agricultural Research and Innovation Centre, Budapest, Hungary.
American Association For The Advancement of Science · USCalifornia Department of Pesticide Regulation · USEuropean Food Safety Authority · ITFederal Office of Consumer Protection and Food Safety · DEHealth Canada · CAJulius Kühn-Institut · DENational Agricultural Research and Innovation Centre · HUOrganisation de Coopération et de Développement Economiques · FRUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) is a biological process in which double-stranded ribonucleic acid (dsRNA) molecules inhibit protein expression. In recent years, the application of dsRNA has been used in the development of agricultural products for pest control. The 2019 Organisation for Economic Cooperation and Development (OECD) Conference on RNAi Based Pesticides ("the Conference") brought together academic, industry, and government experts in various aspects of RNAi to discuss the current state of knowledge and topics to help in developing considerations for risk assessment. The Conference focused on environment, with some discussion of human health. Along with presentations on the use of dsRNA-based products in agriculture, government regulation, risk assessment, and a background on the Draft OECD Working Paper on "Considerations for the Environmental Risk Assessment of the Application of Sprayed or Externally Applied dsRNA-Based Pesticides" ("OECD Working Paper"), the Conference included panel discussions from presenters at the end of each session and a larger discussion session with Conference participants on the environmental fate of dsRNA, non-target organism (NTO) risk assessment, and human health risk assessment. This paper summarizes input from presenters and Conference participants during these discussions. Key considerations from these discussions have already been incorporated into the OECD Working Paper, that once finalized and published, will facilitate regulators in evaluating externally applied dsRNA-based products for potential environmental risks.

Indexed as

double stranded RNAenvironmental risk assessmentgene silencingnon-target organismspest controlregulationRNA interference

Identifiers

PMID32547591
PMCPMC7274041
OpenAlexW3031403127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.