Evidence map›Paper›PMID 32547427›Full record

ArticleFrontiers in psychiatry2020

Enhancing Multi-Center Generalization of Machine Learning-Based Depression Diagnosis From Resting-State fMRI.

Takashi Nakano, Masahiro Takamura, Naho Ichikawa, Go Okada, Yasumasa Okamoto, Makiko Yamada, Tetsuya Suhara, Shigeto Yamawaki, Junichiro Yoshimoto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Takashi NakanoDivision of Information Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Japan.
Masahiro TakamuraDepartment of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan.
Naho IchikawaDepartment of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan.
Go OkadaDepartment of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan.
Yasumasa OkamotoDepartment of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan.
Makiko YamadaInstitute of Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Tetsuya SuharaInstitute of Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Shigeto YamawakiDepartment of Psychiatry and Neurosciences, Hiroshima University, Hiroshima, Japan.
Junichiro YoshimotoDivision of Information Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Japan.
Hiroshima University · JPNara Institute of Science and Technology · JPNational Institutes for Quantum and Radiological Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resting-state fMRI has the potential to help doctors detect abnormal behavior in brain activity and to diagnose patients with depression. However, resting-state fMRI has a bias depending on the scanner site, which makes it difficult to diagnose depression at a new site. In this paper, we propose methods to improve the performance of the diagnosis of major depressive disorder (MDD) at an independent site by reducing the site bias effects using regression. For this, we used a subgroup of healthy subjects of the independent site to regress out site bias. We further improved the classification performance of patients with depression by focusing on melancholic depressive disorder. Our proposed methods would be useful to apply depression classifiers to subjects at completely new sites.

Indexed as

depressionfunctional connectivityharmonizationmachine learningmulti-center fMRIresting state fMRI

Identifiers

PMID32547427
PMCPMC7270328
OpenAlexW3027309739

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.