Evidence map›Paper›PMID 32547382›Full record

ArticleCase reports in oncology

Synchronous and Metachronous Metastatic Breast Cancer, with Different Histology and Opposite Immunophenotype, Treated with Combination of Chemotherapy, Anti-Her2, and Endocrine Therapy: A Case Report.

Giacomina Megaro, Luigi Rossi, Serena Ceddia, Marsela Sinjari, Adele Mannino, Elisa Gozzi, Antonella Cosimati, Martina Brandi, Victoria Bitca, Ilaria Toscani and 2 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giacomina MegaroDepartment of Paediatric Haematology and Oncology, Ospedale Bambin Gesù, Rome, Italy.
Luigi RossiUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Serena CeddiaUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Marsela SinjariUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Adele ManninoUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Elisa GozziUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Antonella CosimatiUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Martina BrandiUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Victoria BitcaUOC of Oncology - ASL Latina - Distretto 1, University of Rome "Sapienza", Aprilia, Italy.
Ilaria ToscaniMedical Oncology Ospedale G. da Saliceto, Piacenza, Italy.
Giuseppe CiminoDepartment of Cellular Biotechnology and Haematology, University of Rome "Sapienza", Rome, Italy.
Silverio TomaoMedical Oncology Unit A Policlinico Umberto I, University of Rome "Sapienza", Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the case of our patient, the synergic action of endocrine therapy and chemotherapy plus dual anti-HER2 combination allowed a complete disease control. Therapy should be scheduled by considering the two cancers as individual entities. The approach to breast cancer is changing from being considered a singular disease to a multiform one, according to current research focused on biological markers such as HER2, ERs, and PRs, with important implications in clinical, prognostic, and therapeutic features.

Indexed as

Bilateral breast cancerCase reportContralateral breastInfiltrating ductal carcinomaInfiltrating lobular carcinomaMetachronous cancerSynchronous cancer

Identifiers

PMID32547382
PMCPMC7275194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.