Evidence map›Paper›PMID 32547245›Full record

ArticleClinical epidemiology2020

Effect of Smoking on Breast Cancer by Adjusting for Smoking Misclassification Bias and Confounders Using a Probabilistic Bias Analysis Method.

Reza Pakzad, Saharnaz Nedjat, Mehdi Yaseri, Hamid Salehiniya, Nasrin Mansournia, Maryam Nazemipour, Mohammad Ali Mansournia

Abstract read
In one paragraph

Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
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16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Reza PakzadDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-8133-3664
Saharnaz NedjatDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi YaseriDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4066-873X
Hamid SalehiniyaSchool of Public Health, Birjand University of Medical Sciences, Birjand, South Khorasan, Iran.
Nasrin MansourniaDepartment of Endocrinology, AJA University of Medical Sciences, Tehran, Iran.
Maryam NazemipourPsychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-5352-6298
Mohammad Ali MansourniaDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3343-2718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to determine the association between smoking and breast cancer after adjusting for smoking misclassification bias and confounders.

methodsIn this case-control study, 1000 women with breast cancer and 1000 healthy controls were selected. Using a probabilistic bias analysis method, the association between smoking and breast cancer was adjusted for the bias resulting from misclassification of smoking secondary to self-reporting as well as a minimally sufficient adjustment set of confounders derived from a causal directed acyclic graph (cDAG). Population attributable fraction (PAF) for smoking was calculated using Miettinen's formula.

resultsWhile the odds ratio (OR) from the conventional logistic regression model between smoking and breast cancer was 0.64 (95% CI: 0.36-1.13), the adjusted ORs from the probabilistic bias analysis were in the ranges of 2.63-2.69 and 1.73-2.83 for non-differential and differential misclassification, respectively. PAF ranges obtained were 1.36-1.72% and 0.62-2.01% using the non-differential bias analysis and differential bias analysis, respectively.

conclusionAfter misclassification correction for smoking, the non-significant negative-adjusted association between smoking and breast cancer changed to a significant positive-adjusted association.

Indexed as

breast cancerMonte Carlo sensitivity analysispopulation attributable fractionprobabilistic bias analysissmoking

Identifiers

PMID32547245
PMCPMC7266328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.