Evidence map›Paper›PMID 32547204›Full record

ReviewCancer management and research2020

The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer.

Changjiu Li, Xian Fu, Huadong He, Chao Chen, Yuyong Wang, Lugeng He

Abstract readReview
In one paragraph

Review in Cancer management and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Emerging Roles of Circular RNAs in Thyroid Cancer.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changjiu Li *Department of Urology, Affiliated Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, People's Republic of China.
Xian Fu *Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou 310006, Zhejiang Province, People's Republic of China.
Huadong HeDepartment of Urology, Affiliated Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, People's Republic of China.ORCID 0000-0002-9570-1373
Chao ChenDepartment of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou 310006, Zhejiang Province, People's Republic of China.
Yuyong WangDepartment of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou 310006, Zhejiang Province, People's Republic of China.
Lugeng HeDepartment of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University, Hangzhou 310006, Zhejiang Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BCa) is the 10th most prevalent malignancy worldwide and remains a crucial cause of cancer-related morbidity and mortality. Circular RNAs (circRNAs), a large class of endogenous non-coding RNAs, contain unique covalent closed structures and their biogenesis and turnover are regulated by multiple factors. Recently, multiple circRNAs have been found to serve as important factors in several biological processes such as tumorigenesis. An increasing amount of research discovered that circRNAs are dysregulated in multiple cancer tissues compared with matched normal tissues, especially in BCa, indicating that circRNAs can act as biomarkers for the diagnosis and prognosis of BCa. In this review, we focus on the biogenesis, properties, turnover, and functions of circRNAs, summarizing their potential functions and clinical implications in BCa.

Indexed as

biogenesisbiomarkerbladder cancercircRNAcircular RNAmicroRNA sponge

Identifiers

PMID32547204
PMCPMC7245432

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.