Evidence map›Paper›PMID 32547144›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

Genetic Association of

Laith N Al-Eitan, Hatem Aman, Rami Alkhatib, Mansour A Alghamdi

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laith N Al-EitanDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-0064-0190
Hatem AmanDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid 22110, Jordan.
Rami AlkhatibDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0003-1635-8624
Mansour A AlghamdiCollege of Medicine, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-6613-1498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the genotypic and allelic association of Src homology 2 B adapter protein 1 ( PATIENTS AND

methodsThree hundred patients were screened, but only 200 adult Jordanian patients diagnosed with T2DM (53.5% male and 46.5% female) have participated in this study. Blood samples were collected from both patients and healthy individuals for DNA extraction according to well-established procedures. Exon 1 and exon 9 of the

resultsTwo novel variations were present in the

conclusionOur findings indicated a strong association between the rs565131715 polymorphism and the risk of T2DM among the Jordanian population. Moreover, our data showed that the rs143212778 polymorphism significantly elevated the danger of T2DM among this population. This study reveals the first data regarding the

Indexed as

ArabJordanSH2B1type 2 diabetes mellitus

Identifiers

PMID32547144
PMCPMC7250702

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.