Evidence map›Paper›PMID 32547026›Full record

ReviewInternational journal of nanomedicine2020

Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases.

Rajasekharreddy Pala, V T Anju, Madhu Dyavaiah, Siddhardha Busi, Surya M Nauli

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 183 citations in OpenAlex.

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  14. Molecular mechanisms and intervention approaches of heart failure (Review).International journal of molecular medicine · 2025
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  19. Oxidative Stress in Cardiovascular Diseases: Mechanisms and Exploring Advanced Therapies.Cardiovascular & hematological agents in medicinal chemistry · 2025
    Review
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Rajasekharreddy PalaDepartment of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA.ORCID 0000-0001-9787-1053
V T AnjuDepartment of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India.ORCID 0000-0001-6532-1946
Madhu DyavaiahDepartment of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India.
Siddhardha BusiDepartment of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, India.ORCID 0000-0001-9670-2100
Surya M NauliDepartment of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA.ORCID 0000-0002-9676-0287
Pondicherry University · INChapman University · US

Funding

The signaling mechanism of primary cilia in aneurysm preventionR56HL131577 · NHLBI · CHAPMAN UNIVERSITY · PI NAULI, SURYA · 2017 to 2017
$345k
NHLBI NIH HHS R56 HL131577
6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.

Indexed as

Drug Delivery SystemsCardiovascular DiseasesHumansNanomedicineNanoparticlesRisk FactorsTreatment Outcomecardiovascular diseasesnanocarriersnanomedicinenanoparticlesnanosciencetreatment

Identifiers

PMID32547026
PMCPMC7266400
OpenAlexW3032763440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.