Evidence map›Paper›PMID 32547018›Full record

ArticleInternational journal of nanomedicine2020

Synergistic Effects of Physicochemical Parameters on Bio-Fabrication of Mint Silver Nanoparticles: Structural Evaluation and Action Against HCT116 Colon Cancer Cells.

Bilal Javed, Zia-Ur-Rehman Mashwani

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 61 citations in OpenAlex.

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  18. 2-DimensionalFrontiers in bioengineering and biotechnology · 2022
    Article
  19. Biosynthesis of silver nanoparticles using extract ofFrontiers in molecular biosciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Bilal JavedRoy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA.ORCID 0000-0002-9566-1498
Zia-Ur-Rehman MashwaniDepartment of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab 46300, Pakistan.ORCID 0000-0003-4222-7708
Pir Mehr Ali Shah Arid Agriculture University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysicochemical parameters such as temperature, pH, the concentration of the AgNO

methodsPlant-mediated method was used for the bio-fabrication and stabilization of AgNPs. Reaction parameters were arranged, and surface plasmon resonance (SPR) bands of AgNPs were collected by using a UV-Visible spectrophotometer. NPs were characterized structurally and optically by using SEM, AFM, EDX and DLS techniques. AgNPs and plant aqueous extract were tested against HCT116 colon cancer cells by using SRB assay, Annexin V assay and cell cycle analysis.

resultsSpectrophotometric comparison of various reaction conditions manifested that 5 mM of AgNO

conclusionThese findings explain the synergistic effects of physicochemical parameters to optimize the phytosynthesis of biocompatible AgNPs to overcome the limitations of conventional chemotherapeutic treatments of colon cancer cells.

Indexed as

Antineoplastic AgentsCatalysisCell CycleColonic NeoplasmsHCT116 CellsHumansHydrogen-Ion ConcentrationInhibitory Concentration 50MenthaMetal NanoparticlesParticle SizePlant ExtractsSilverSpectrophotometry, UltravioletTemperatureAntineoplastic AgentsPlant ExtractsSilveranticancercell cycle analysiscolorectal cancergreen synthesisMentha arvensisreaction dynamics

Identifiers

PMID32547018
PMCPMC7250703
OpenAlexW3026077689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.