Evidence map›Paper›PMID 32546977›Full record

ArticlePatient preference and adherence2020

Using a Discrete-Choice Experiment in a Decision Aid to Nudge Patients Towards Value-Concordant Treatment Choices in Rheumatoid Arthritis: A Proof-of-Concept Study.

Glen S Hazlewood, Deborah A Marshall, Claire E H Barber, Linda C Li, Cheryl Barnabe, Vivian Bykerk, Peter Tugwell, Pauline M Hull, Nick Bansback

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Clarifying Values: An Updated and Expanded Systematic Review and Meta-Analysis.Medical decision making : an international journal of the Society for Medical Decision Making · 2021
    Pooled it
  3. Trial
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  7. Risk-Adapted Breast Screening for Women at Low Predicted Risk of Breast Cancer: An Online Discrete Choice Experiment.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Glen S HazlewoodDepartments of Medicine and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.ORCID 0000-0001-7709-3741
Deborah A MarshallDepartments of Medicine and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Claire E H BarberDepartments of Medicine and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Linda C LiArthritis Research Canada, Vancouver, BC, Canada.ORCID 0000-0001-6280-0511
Cheryl BarnabeDepartments of Medicine and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.ORCID 0000-0003-3761-237X
Vivian BykerkWeill Cornell Medical College, Cornell University, New York, NY, USA.ORCID 0000-0002-1219-3845
Peter TugwellDepartment of Medicine, Department of Epidemiology and Community Medicine, Canada Research Chair, University of Ottawa, Institute of Population Health, Ottawa, Canada.
Pauline M HullUniversity of Calgary, Calgary, Canada.
Nick BansbackArthritis Research Canada, Vancouver, BC, Canada.
University of Calgary · CAHospital for Special Surgery · USResearch Canada · CAUniversity of British Columbia · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate, in a proof-of-concept study, a decision aid that incorporates hypothetical choices in the form of a discrete-choice experiment (DCE), to help patients with early rheumatoid arthritis (RA) understand their values and nudge them towards a value-centric decision between methotrexate and triple therapy (a combination of methotrexate, sulphasalazine and hydroxychloroquine). PATIENTS AND

methodsIn the decision aid, patients completed a series of 6 DCE choice tasks. Based on the patient's pattern of responses, we calculated his/her probability of choosing each treatment, using data from a prior DCE. Following pilot testing, we conducted a cross-sectional study to determine the agreement between the predicted and final stated preference, as a measure of value concordance. Secondary outcomes including time to completion and usability were also evaluated.

resultsPilot testing was completed with 10 patients and adjustments were made. We then recruited 29 patients to complete the survey: median age 57, 55% female. The patients were all taking treatment and had well-controlled disease. The predicted treatment agreed with the final treatment chosen by the patient 21/29 times (72%), similar to the expected agreement from the mean of the predicted probabilities (68%). Triple therapy was the predicted treatment 24/29 times (83%) and chosen 20/29 (69%) times. Half of the patients (51%) agreed that completing the choice questions helped them to understand their preferences (38% neutral, 10% disagreed). The tool took an average of 15 minutes to complete, and median usability scores were 55 (system usability scale) indicating "OK" usability.

conclusionUsing a DCE as a value-clarification task within a decision aid is feasible, with promising potential to help nudge patients towards a value-centric decision. Usability testing suggests further modifications are needed prior to implementation, perhaps by having the DCE exercises as an "add-on" to a simpler decision aid.

Indexed as

conjoint analysisdecision toolmethotrexatevalue concordance

Identifiers

PMID32546977
PMCPMC7244245
OpenAlexW3025536215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.