Evidence map›Paper›PMID 32546917›Full record

ArticleVeterinary world2019

Okereke Henry Nnamdi, Udegbunam Rita Ijeoma, Nwobi Lotanna Gilbert, Ezeobialu Henry Toochukwu, Udegbunam Sunday Ositadinma

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Okereke Henry NnamdiDepartment of Veterinary Surgery, Faculty of Veterinary Medicine, University of Nigeria, Enugu State, Nigeria.
Udegbunam Rita IjeomaDepartment of Veterinary Surgery, Faculty of Veterinary Medicine, University of Nigeria, Enugu State, Nigeria.
Nwobi Lotanna GilbertDepartment of Veterinary Physiology and Pharmacology, Faculty of Veterinary Medicine, University of Nigeria, Enugu State, Nigeria.
Ezeobialu Henry ToochukwuDepartment of Veterinary Surgery, Faculty of Veterinary Medicine, University of Nigeria, Enugu State, Nigeria.
Udegbunam Sunday OsitadinmaDepartment of Veterinary Surgery, Faculty of Veterinary Medicine, University of Nigeria, Enugu State, Nigeria.
University of Nigeria · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimStored blood is continuously exposed to oxidative stress, which affects its antioxidant protective system. Erythrocytes are naturally armed with antioxidant protective capacity. Blood antioxidant system functions to protect the blood cells against oxidative damage by free radicals. However, during storage, blood is continuously exposed to oxidative stress, which affects its antioxidant system. The aim of this work was to investigate alteration in malondialdehyde (MDA) levels, reduced glutathione (glutathione reductase [GSH-Rd]), catalase (CAT), and superoxide dismutase (SOD) activities in stored donkey blood. MATERIALS AND

methodsBlood (250 ml) was drawn from four clinically healthy donkeys into citrate phosphate dextrose adenine 1 blood bags and preserved at 4°C. MDA, GSH-Rd, CAT, and SOD activities were assayed by colorimetric methods, over a period of 42 days.

resultsThe result showed that SOD enzyme activities significantly (p<0.05) increased by day 7 post-storage (PS) while MDA levels significantly (p<0.05) increased by day 21 PS. However, activities of GSH-Rd and CAT enzymes decreased (p<0.05) by day 21 PS. Pearson's product-moment correlation showed a negative correlation between the levels of MDA and enzymatic antioxidant markers (CAT and GSH-Rd).

conclusionThe findings revealed that GSH-Rd and CAT are the primary antioxidant defense markers in donkey red blood cells. The observed alterations in these principal antioxidants suggest a 14days optimum keeping time of donkey blood for blood banking purposes.

Indexed as

bloodcitrate phosphate dextrose adenine 1donkeymalondialdehydesuperoxide dismutase

Identifiers

PMID32546917
PMCPMC7245712
OpenAlexW3016951418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.