Evidence map›Paper›PMID 32546691›Full record

ArticleScientific reports2020

Three-dimensional real time imaging of amyloid β aggregation on living cells.

Masahiro Kuragano, Ryota Yamashita, Yusaku Chikai, Ryota Kitamura, Kiyotaka Tokuraku

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  7. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Masahiro KuraganoGraduate School of Engineering, Muroran Institute of Technology, 27-1 Mizumoto, Muroran, 050-8585, Japan.
Ryota YamashitaGraduate School of Engineering, Muroran Institute of Technology, 27-1 Mizumoto, Muroran, 050-8585, Japan.
Yusaku ChikaiGraduate School of Engineering, Muroran Institute of Technology, 27-1 Mizumoto, Muroran, 050-8585, Japan.
Ryota KitamuraGraduate School of Engineering, Muroran Institute of Technology, 27-1 Mizumoto, Muroran, 050-8585, Japan.
Kiyotaka TokurakuGraduate School of Engineering, Muroran Institute of Technology, 27-1 Mizumoto, Muroran, 050-8585, Japan. tokuraku@mmm.muroran-it.ac.jp.
Muroran Institute of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive disorder of the brain that gradually decreases thinking, memory, and language abilities. The aggregation process of amyloid β (Aβ) is a key step in the expression of its neurocytotoxicity and development of AD because Aβ aggregation and accumulation around neuronal cells induces cell death. However, the molecular mechanism underlying the neurocytotoxicity and cell death by Aβ aggregation has not been clearly elucidated. In this study, we successfully visualized real-time process of Aβ

Indexed as

Alzheimer DiseaseAmyloidAmyloid beta-PeptidesAnimalsBrainImaging, Three-DimensionalMemoryMicroscopy, ConfocalNeuronsPC12 CellsPeptide FragmentsPlaque, AmyloidProtein Aggregation, PathologicalRatsAmyloidAmyloid beta-PeptidesPeptide Fragments

Identifiers

PMID32546691
PMCPMC7297742
OpenAlexW3035082914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.