Evidence map›Paper›PMID 32546616›Full record

ArticlemBio2020

Convergent Evolution of Neutralizing Antibodies to Staphylococcus aureus γ-Hemolysin C That Recognize an Immunodominant Primary Sequence-Dependent B-Cell Epitope.

David N Hernandez, Kayan Tam, Bo Shopsin, Emily E Radke, Karen Law, Timothy Cardozo, Victor J Torres, Gregg J Silverman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Emerging Strategies to Combat β-Lactamase Producing ESKAPE Pathogens.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David N HernandezDivision of Rheumatology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
Kayan TamSackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, New York, USA.
Bo ShopsinDivision of Infectious Diseases and Immunology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
Emily E RadkeDivision of Rheumatology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
Karen LawDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, USA.
Timothy CardozoDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, USA.
Victor J TorresDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Gregg J SilvermanDivision of Rheumatology, Department of Medicine, New York University School of Medicine, New York, New York, USA Gregg.silverman@nyumc.org.ORCID 0000-0001-9480-9457
New York University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
Translational Center of Molecular Profiling in Preclinical and Established Lupus (COMPEL)P50AR070591 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI IZMIRLY, PETER · 2017 to 2021
$6.7M
Mechanistic Studies Of The Staphylococcus aureus LukAB CytotoxinR01AI099394 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Victor J. Torres · 2013 to 2026
$6.1M
Contribution of LukED to Staphylococcus aureus pathobiologyR01AI105129 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI TORRES, VICTOR J. · 2014 to 2023
$4.9M
Mechanisms of MRSA intestinal colonizationR01AI140754 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO · 2020 to 2024
$3.5M
Host-pathogen interactions during hospital adaptation of MRSAR01AI137336 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, YANAI, ITAI · 2019 to 2022
$3.3M
Training in Pharmacological SciencesT32GM066704 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BACH, ERIKA A · 2004 to 2018
$2.6M
NCI NIH HHS P30 CA016087NIAID NIH HHS HHSN272201400019CNIAID NIH HHS R01 AI099394NIAID NIH HHS R01 AI105129NIAID NIH HHS R01 AI137336NIAID NIH HHS R01 AI140754NIAID NIH HHS T32 AI007180NIAMS NIH HHS P50 AR070591NIGMS NIH HHS T32 GM066704
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntibodies, BacterialAntibodies, NeutralizingBacterial ProteinsBacterial ToxinsEpitope MappingEpitopes, B-LymphocyteExotoxinsFemaleHemolysin ProteinsHumansImmunodominant EpitopesImmunoglobulin GLeukocidinsMiceMice, Inbred BALB CAntibodies, BacterialAntibodies, NeutralizingBacterial ProteinsBacterial ToxinsEpitopes, B-LymphocyteExotoxinsgamma-hemolysin, Staphylococcus aureusHemolysin ProteinsImmunodominant EpitopesImmunoglobulin GLeukocidinsleukotoxinPeptide LibraryVirulence Factorsantibody functionbacteriophage displayB cell epitopebiotechnologyepitopeexotoxinsleukocidinprotectionStaphylococcus aureusvaccines

Identifiers

PMID32546616
PMCPMC7298706
OpenAlexW3035188775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.