Evidence map›Paper›PMID 32546263›Full record

ReviewVeterinary research2020

Coinfections and their molecular consequences in the porcine respiratory tract.

Georges Saade, Céline Deblanc, Juliette Bougon, Corinne Marois-Créhan, Christelle Fablet, Gaël Auray, Catherine Belloc, Mily Leblanc-Maridor, Carl A Gagnon, Jianzhong Zhu and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 232 citations in OpenAlex.

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  16. A Triplex Real-Time PCR Assay for Simultaneous Detection ofTransboundary and emerging diseases · 2026
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87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Georges SaadeINRAE, Oniris, BIOEPAR, 44300, Nantes, France.
Céline DeblancSwine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP 53, 22440, Ploufragan, France.
Juliette BougonSwine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP 53, 22440, Ploufragan, France.
Corinne Marois-CréhanMycoplasmology, Bacteriology and Antibiotics Resistance Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP 53, 22440, Ploufragan, France.
Christelle FabletEpidemiology Health and Welfare Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP 53, 22440, Ploufragan, France.
Gaël AurayInstitute of Virology and Immunology (IVI), Sensemattstrasse 293, 3147, Mittelhäusern, Switzerland.
Catherine BellocINRAE, Oniris, BIOEPAR, 44300, Nantes, France.
Mily Leblanc-MaridorINRAE, Oniris, BIOEPAR, 44300, Nantes, France.
Carl A GagnonSwine and Poultry Infectious Diseases Research Center, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.
Jianzhong ZhuCollege of Veterinary Medicine, Comparative Medicine Research Institute, Yangzhou University, Yangzhou, 225009, China.
Marcelo GottschalkSwine and Poultry Infectious Diseases Research Center, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.
Artur SummerfieldInstitute of Virology and Immunology (IVI), Sensemattstrasse 293, 3147, Mittelhäusern, Switzerland.
Gaëlle SimonSwine Virology Immunology Unit, Ploufragan-Plouzané-Niort Laboratory, ANSES, BP 53, 22440, Ploufragan, France.
Nicolas BerthoINRAE, Oniris, BIOEPAR, 44300, Nantes, France.
François MeurensINRAE, Oniris, BIOEPAR, 44300, Nantes, France. francois.meurens@inrae.fr.ORCID http://orcid.org/0000-0002-0353-4871
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRUniversité de Montréal · CAUniversity of Bern · CHYangzhou University · CN

Funding

Association Philippe Jabre PhD grantConseil Régional des Pays de la Loire Establishment grant
6 · The paper itself

Abstract

Understudied, coinfections are more frequent in pig farms than single infections. In pigs, the term "Porcine Respiratory Disease Complex" (PRDC) is often used to describe coinfections involving viruses such as swine Influenza A Virus (swIAV), Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and Porcine CircoVirus type 2 (PCV2) as well as bacteria like Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae and Bordetella bronchiseptica. The clinical outcome of the various coinfection or superinfection situations is usually assessed in the studies while in most of cases there is no clear elucidation of the fine mechanisms shaping the complex interactions occurring between microorganisms. In this comprehensive review, we aimed at identifying the studies dealing with coinfections or superinfections in the pig respiratory tract and at presenting the interactions between pathogens and, when possible, the mechanisms controlling them. Coinfections and superinfections involving viruses and bacteria were considered while research articles including protozoan and fungi were excluded. We discuss the main limitations complicating the interpretation of coinfection/superinfection studies, and the high potential perspectives in this fascinating research field, which is expecting to gain more and more interest in the next years for the obvious benefit of animal health.

Indexed as

AnimalsCoinfectionRespiratory Tract DiseasesSuperinfectionSus scrofaSwineSwine Diseases

Identifiers

PMID32546263
PMCPMC7296899
OpenAlexW3035564235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.