Evidence map›Paper›PMID 32546210›Full record

ArticleAntimicrobial resistance and infection control2020

A silent outbreak of vancomycin-resistant Enterococcus faecium in a neonatal intensive care unit.

Ronella Marom, Dror Mandel, Alon Haham, Irit Berger, Amit Ovental, Craig Raskind, Galia Grisaru-Soen, Amos Adler, Jonathan Lellouche, David Schwartz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Vancomycin-resistantInfection prevention in practice · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Carriage of vancomycin-resistantInfection control and hospital epidemiology · 2023
    Article
  8. Article
  9. Frequency and co-colonization of vancomycin-resistantNew microbes and new infections · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ronella MaromDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel. marom.ronella@gmail.com.
Dror MandelDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel.
Alon HahamDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel.
Irit BergerDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel.
Amit OventalDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel.
Craig RaskindDepartment of Neonatology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Weizmann Street, 6423906, Tel-Aviv, Israel.
Galia Grisaru-SoenSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Amos AdlerSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jonathan LelloucheNational Laboratory for Antibiotic Resistance and Investigation of Outbreaks in Medical Institutions, National Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
David SchwartzNational Laboratory for Antibiotic Resistance and Investigation of Outbreaks in Medical Institutions, National Institute for Antibiotic Resistance and Infection Control, Ministry of Health, Tel Aviv, Israel.
Yehuda CarmeliSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Vered SchechnerSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv Sourasky Medical Center · ILIsrael Ministry of Health · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the containment of a widespread silent outbreak of vancomycin-resistant Enterococcus faecium (VRE-fm) in the Tel-Aviv Medical Center (TASMC) neonatal intensive care unit (NICU).

methodsSetting - an NICU, participants - 49 cases of VRE-fm-colonized neonatal inpatients.

resultsA newborn was transferred from the TASMC NICU to another hospital and screened positive for VRE-fm upon arrival. All TASMC NICU patients were then immediately screened for VRE and 21/38 newborns were identified as VRE carriers. Interventional measures were strictly enforced. By the end of the outbreak, 49 cases of VRE carriage had been identified. There were no VRE clinical infections. The source of the outbreak was not identified.

conclusionOur study highlights the importance of screening implementation in a NICU setting since this outbreak could have been prevented by active screening of all out-born transfer patients and by having adopted mandatory screening into the NICU's routine procedures. Screening for multi-drug resistant organisms upon admission of all transferred patients to the NICU has been implemented.

Indexed as

Vancomycin ResistanceCross InfectionDisease OutbreaksDrug Resistance, Multiple, BacterialEnterococcus faeciumGram-Positive Bacterial InfectionsHumansInfant, NewbornInfection ControlIntensive Care Units, NeonatalIsraelInfectionNeonatal intensive care unitNeonateOutbreakScreeningVancomycin-resistant Enterococcus faecium

Identifiers

PMID32546210
PMCPMC7298964
OpenAlexW3035165398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.