Evidence map›Paper›PMID 32546136›Full record

ArticleBMC psychiatry2020

The Binge Eating Genetics Initiative (BEGIN): study protocol.

Cynthia M Bulik, Jonathan E Butner, Jenna Tregarthen, Laura M Thornton, Rachael E Flatt, Tosha Smith, Ian M Carroll, Brian R W Baucom, Pascal R Deboeck

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04162574 (Predicting Binge and Purge Episodes From Passive and Active Apple Watch Data Using a Dynamical Systems Approach), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04162574 completednot on this map

Predicting Binge and Purge Episodes From Passive and Active Apple Watch Data Using a Dynamical Systems Approach

Typeobservational_patient_registrySponsorUniversity of North Carolina, Chapel HillRan2017 to 2021Enrolled1,166ConditionsBinge-Eating Disorder, Bulimia NervosaArmsRecovery Record
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Relationship Between Intensive Passive Data Signals and Patterns of Binge-Eating Behaviors: From a Dynamical-System Approach.Clinical psychological science : a journal of the Association for Psychological Science · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC, 27599-7160, USA. cbulik@med.unc.edu.ORCID 0000-0001-7772-3264
Jonathan E ButnerDepartment of Psychology, University of Utah, Salt Lake City, UT, USA.
Jenna TregarthenRecovery Record, San Francisco, CA, USA.
Laura M ThorntonDepartment of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC, 27599-7160, USA.
Rachael E FlattDepartment of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC, 27599-7160, USA.
Tosha SmithDepartment of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC, 27599-7160, USA.
Ian M CarrollDepartment of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Brian R W BaucomDepartment of Psychology, University of Utah, Salt Lake City, UT, USA.
Pascal R DeboeckDepartment of Psychology, University of Utah, Salt Lake City, UT, USA.
University of North Carolina at Chapel Hill · USUniversity of Utah · USRecovery Record (United States) · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
Predicting Binge and Purge Episodes from Passive and Active Apple Watch Data Using a Dynamical Systems ApproachR01MH119084 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, BUTNER, JONATHAN · 2019 to 2022
$2.8M
1/7 Psychiatric Genomics Consortium: Finding actionable variationU01MH109528 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULLIVAN, PATRICK F · 2016 to 2020
$2.5M
NIDDK NIH HHS P30 DK056350NIMH NIH HHS R01 MH119084NIMH NIH HHS U01 MH109528
6 · The paper itself

Abstract

backgroundThe Binge Eating Genetics Initiative (BEGIN) is a multipronged investigation examining the interplay of genomic, gut microbiota, and behavioral factors in bulimia nervosa and binge-eating disorder.

methods1000 individuals who meet current diagnostic criteria for bulimia nervosa or binge-eating disorder are being recruited to collect saliva samples for genotyping, fecal sampling for microbiota characterization, and recording of 30 days of passive data and behavioral phenotyping related to eating disorders using the app Recovery Record adapted for the Apple Watch. DISCUSSION: BEGIN examines the interplay of genomic, gut microbiota, and behavioral factors to explore etiology and develop predictors of risk, course of illness, and response to treatment in bulimia nervosa and binge-eating disorder. We will optimize the richness and longitudinal structure of deep passive and active phenotypic data to lay the foundation for a personalized precision medicine approach enabling just-in-time interventions that will allow individuals to disrupt eating disorder behaviors in real time before they occur.

trial registrationThe ClinicalTrials.gov identifier is NCT04162574. November 14, 2019, Retrospectively Registered.

Indexed as

Binge-Eating DisorderBulimiaBulimia NervosaFeeding and Eating DisordersFeeding BehaviorHumansBinge eatingEating disordersGeneticsMicrobiomeMobile applicationWearable technology

Identifiers

PMID32546136
PMCPMC7298834
OpenAlexW3034941444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.