ArticleInternational journal of environmental research and public health2020
Multimorbidity Patterns in the General Population: Results from the EpiChron Cohort Study.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prevalence and representation of comorbidities and multimorbidity in randomised controlled trials in sepsis or septic shock: a systematic review.Critical care (London, England) · 2026Pooled it
- A systematic review and meta-analysis of disease clusters in multimorbidity.Nature communications · 2025Pooled it
- Social determinants of multimorbidity patterns: A systematic review.Frontiers in public health · 2023Pooled it
- Disparities in the Prevalence of Childhood Obesity-Related Comorbidities: A Systematic Review.Frontiers in public health · 2022Pooled it
- Clarity in Reporting Multiple Long-Term Conditions in Research: The Need for Consistency and Consensus.Diabetes, obesity & metabolism · 2026Article
- Training needs and curricular priorities for managing multimorbidity in Spanish primary care: findings from a national exploratory online survey.BMC primary care · 2026Article
- Relevance of Kidney-Metabolic Multimorbidity Pattern to Metabolic Health and Mortality Among Elderly Inpatients in China.Food science & nutrition · 2026Article
- Multimorbidity Patterns and Obesity Among Americans Turning Forty.American journal of health promotion : AJHP · 2026Article
- The Relationships Between MASLD, Extrahepatic Multimorbidity, and All-Cause Mortality in the UK Biobank Cohort.The Journal of clinical endocrinology and metabolism · 2025Article
- Exploring the genetic architecture of multiple long-term conditions using a genome-wide association study in the UK Biobank population.Scientific reports · 2025Article
- Inequalities in multimorbidity between native-born and immigrant older adults across Europe.European journal of ageing · 2025Article
- Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015-2018.BMC public health · 2025Article
- Temporal multimorbidity patterns and cluster identification: a longitudinal analysis of administrative data.BMC medicine · 2025Article
- Prospective association between plasma amino acids and three Multimorbidity patterns in older adults.Scientific reports · 2025Article
- Prevalence of multimorbidity among urban-rural older adults in Mongolia: a cross-sectional study.BMC public health · 2025Article
- Electronic Health Records: A Gateway to AI-Driven Multimorbidity Solutions-A Comprehensive Systematic Review.Journal of clinical medicine · 2025Review
- Multimorbidity patterns of mental disorders and physical diseases of adults in northeast China: a cross-sectional network analysis.Epidemiology and psychiatric sciences · 2025Article
- Charting the Pathways of Cardiometabolic Multimorbidity: A Systematic Review of Clinical Trajectories.Journal of clinical medicine · 2025Review
- Multimorbidity in Patients with Chronic Liver Disease: A Population-Based Study in the EpiChron Cohort, Spain.Journal of clinical medicine · 2024Article
- Multimorbidity in Incident Heart Failure: Characterisation and Impact on 1-Year Outcomes.Journal of clinical medicine · 2024Article
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11 authors.
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Abstract
The correct management of patients with multimorbidity remains one of the main challenges for healthcare systems worldwide. In this study, we analyze the existence of multimorbidity patterns in the general population based on gender and age. We conducted a cross-sectional study of individuals of all ages from the EpiChron Cohort, Spain (1,253,292 subjects), and analyzed the presence of systematic associations among chronic disease diagnoses using exploratory factor analysis. We identified and clinically described a total of 14 different multimorbidity patterns (12 in women and 12 in men), with some relevant differences in the functions of age and gender. The number and complexity of the patterns was shown to increase with age in both genders. We identified associations of circulatory diseases with respiratory disorders, chronic musculoskeletal diseases with depression and anxiety, and a very consistent pattern of conditions whose co-occurrence is known as metabolic syndrome (hypertension, diabetes, obesity, and dyslipidaemia), among others. Our results demonstrate the potential of using real-world data to conduct large-scale epidemiological studies to assess the complex interactions among chronic conditions. This could be useful in designing clinical interventions for patients with multimorbidity, as well as recommendations for healthcare professionals on how to handle these types of patients in clinical practice.
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