Evidence map›Paper›PMID 32545856›Full record

ArticleJournal of clinical medicine2020

The Impact of Gastric Juice pH on the Intraluminal Therapy for

Yu-Chio Wang, Yen-Po Chen, Cheng-Yu Ho, Ting-Wen Liu, Cheng-Hsin Chu, Horng-Yuan Wang, Tai-Cherng Liou

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03124420 phase4completednot on this map

Intraluminal Therapy for Helicobacter Pylori Infection

TypeinterventionalSponsorMackay Memorial HospitalRan2017 to 2018Enrolled100ConditionsHelicobacter Pylori InfectionArmsLansoprazole, Amoxicillin, Clarithromycin
NCT04901663 phase4completednot on this mapstarted 2021, after this paper: background citation

Comparison of Vonoprazan and Amoxicillin Dual Therapy With Standard Triple Therapy With Proton Pump Inhibitor for Helicobacter Pylori Eradication; a Randomized Control Trial

TypeinterventionalSponsorDow University of Health SciencesRan2021 to 2021Enrolled179ConditionsHelicobacter Pylori InfectionArmsOmeprazole 20 MG Capsule, Amoxicillin 1000 MG, Clarithromycin 500 MG, Vonoprazan 20 MG, Amoxicillin 1000 MG
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Current paradigms in the management of refractory Helicobacter pylori infection.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Review
  5. Intraluminal Therapy forBiomedicines · 2023
    Article
  6. Article
  7. Article
  8. [First-Line Eradication ofActa gastroenterologica Latinoamericana
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-Chio WangDepartment of General Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Yen-Po ChenDepartment of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan.
Cheng-Yu HoDepartment of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan.
Ting-Wen LiuDepartment of General Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Cheng-Hsin ChuDepartment of General Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan.
Horng-Yuan WangDepartment of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan.
Tai-Cherng LiouDepartment of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan.ORCID 0000-0002-6681-3819

Funding

Biomedical Development Center and Innovation & Incubation Center, MacKay Memorial Hospital BMD-105-008 and BMD-106-003
6 · The paper itself

Abstract

background

aimsTo detect gastric juice pH and evaluate its impact on the success rate of ILTHPI.

methodsWe enrolled 324 patients with upper abdominal discomfort for endoscopic examinations. Among them, 13C-urea breath test was positive in 218 patients, where 100 underwent ILTHPI, and negative in 106. All patients had their gastric juice pH detected and set into three ranges, including normal acidity (pH < 4.0), low-level hypoacidity (pH 4.0-5.5), and high-level hypoacidity (pH ≥ 6.0). The impact of gastric juice pH on the success rate of ILTHPI was evaluated.

resultsDistribution of pH level showed no significant difference between two groups of

conclusionsDetection of gastric juice pH in ILTHPI is extremely important. Rapid control of stomach pH at or above 4 for patients prior to ILTHPI is strongly recommended. (NCT03124420).

Indexed as

acidityendoscopygastric juiceHelicobacter pyloritherapy

Identifiers

PMID32545856
PMCPMC7356802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.