Evidence map›Paper›PMID 32545830›Full record

ArticleJournal of clinical medicine2020

Involvement of the 14-3-3 Gene Family in Autism Spectrum Disorder and Schizophrenia: Genetics, Transcriptomics and Functional Analyses.

Bàrbara Torrico, Ester Antón-Galindo, Noèlia Fernàndez-Castillo, Eva Rojo-Francàs, Sadaf Ghorbani, Laura Pineda-Cirera, Amaia Hervás, Isabel Rueda, Estefanía Moreno, Janice M Fullerton and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Autism spectrum disorder and schizophrenia: An updated conceptual review.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  2. Subcellular mass spectrometry reveals proteome remodeling in an asymmetrically dividing (frog) embryonic stem cell.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  6. Review
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  8. The 14-3-3 Protein Family and Schizophrenia.Frontiers in molecular neuroscience · 2022
    Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 5 countries.

Bàrbara TorricoDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.
Ester Antón-GalindoDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0002-7016-8189
Noèlia Fernàndez-CastilloDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0001-9948-0312
Eva Rojo-FrancàsDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0001-6856-5751
Sadaf GhorbaniCentre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, N5009 Bergen, Norway.
Laura Pineda-CireraDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0002-4701-7657
Amaia HervásChild and Adolescent Mental Health Unit, Hospital Universitari Mútua de Terrassa, 08221 Terrassa, Spain.
Isabel RuedaChild and Adolescent Mental Health Unit, Hospital Universitari Mútua de Terrassa, 08221 Terrassa, Spain.
Estefanía MorenoInstitut de Biomedicina de la Universitat de Barcelona (IBUB), 08028 Barcelona, Spain.ORCID 0000-0002-2491-5753
Janice M FullertonNeuroscience Research Australia, Sydney, NSW 2031, Australia.ORCID 0000-0003-4014-4490
Vicent CasadóInstitut de Biomedicina de la Universitat de Barcelona (IBUB), 08028 Barcelona, Spain.
Jan K BuitelaarDepartment of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 HR Nijmegen, The Netherlands.
Nanda RommelseKarakter Child and Adolescent Psychiatry University Centre, 6525 GC Nijmegen, The Netherlands.
Barbara FrankeDepartment of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, 6525 HR Nijmegen, The Netherlands.ORCID 0000-0003-4375-6572
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Andreas G ChiocchettiDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence Frankfurt, JW Goethe University, 60323 Frankfurt am Main, Germany.
Christine FreitagDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence Frankfurt, JW Goethe University, 60323 Frankfurt am Main, Germany.
Rune KleppeCentre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, N5009 Bergen, Norway.ORCID 0000-0002-6086-755X
Jan HaavikCentre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, N5009 Bergen, Norway.
Claudio TomaDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0003-3901-7507
Bru CormandDepartament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Prevosti Building, floor 2, Av. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0001-5318-4382
Instituto de Salud Carlos III · ESGoethe University Frankfurt · DERadboud University Nijmegen · NLInstitut de Biomedicina de la Universitat de BarcelonaMútua Terrassa · ESUniversity of Bergen · NOUNSW Sydney · AUHaukeland University Hospital · NO

Funding

AGAUR 2017SGR738, 2017SGR1497Australian National Medical and Health Research Council (NHMRC) Project Grant 1063960 and 1066177, and Program Grant 1037196European Union H2020 Program (H2020/2014-2020) 667302 (CoCA) and 643051 (MiND)FEDER SAF2015-68341-R, SAF2017-87629-R, RTI2018-100968-B-I00Fundació La Marató de TV3 092010
6 · The paper itself

Abstract

The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed

Indexed as

14-3-3 gene familyautismcommon variantsrare variantsschizophreniatranscriptomicsYWHAEYWHAZ

Identifiers

PMID32545830
PMCPMC7356291
OpenAlexW3034391472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.