ArticleJournal of clinical medicine2020
Effects of Prolonged Type 2 Diabetes on the Inner Retinal Layer and Macular Microvasculature: An Optical Coherence Tomography Angiography Study.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
- Longitudinal changes in each retinal layer thickness in diabetic retinopathy patients treated with pan-retinal photocoagulation.Eye (London, England) · 2026Article
- Macular perfusion alterations in people with recent-onset diabetes and novel diabetes subtypes.Diabetologia · 2025Observational
- Retinochoroidal and Optic Nerve Head Microstructural and Microvascular Age-Related Changes in Healthy Eyes.Diagnostics (Basel, Switzerland) · 2025Article
- Association Between Contrast Sensitivity and Ganglion Cell-Inner Plexiform Layer Thickness After Resolution of Macular Edema Due to Branch Retinal Vein Occlusion.Journal of clinical medicine · 2025Article
- Impact of systemic hypertension on inner retinal layer thickness and macular microvasculature in patients with diabetic retinopathy.Acta diabetologica · 2025Article
- Glycemic Control and Retinal Microvascular Changes in Type 2 Diabetes Mellitus Patients without Clinical Retinopathy.Diabetes & metabolism journal · 2024Observational
- Ocular microvascular complications in diabetic retinopathy: insights from machine learning.BMJ open diabetes research & care · 2024Article
- Comparison of Choroidal Vascularity Index, Retinal, and Optic Nerve Changes in Diabetes Mellitus Patients Without Diabetic Retinopathy.Beyoglu eye journal · 2024Article
- Changes in peripapillary microvasculature in patients with type 2 diabetes patients: effect of systemic hypertension.Scientific reports · 2023Article
- Retinal Vascular Density Change in Patients With Aortic Valve Regurgitation.Cardiology research · 2023Article
- Analyses of the ratio of ganglion cell-inner plexiform layer thickness to vessel density according to age in healthy eyes.PloS one · 2023Article
- Superficial capillary plexus vessel density/deep capillary plexus vessel density ratio in healthy eyes.BMC ophthalmology · 2022Article
- Different characteristics of retinal damage between chronic hypertension and hypertensive retinopathy.Scientific reports · 2022Article
- Choroidal and Retinal Thicknesses in Type 2 Diabetes Mellitus with Moderate Diabetic Retinopathy Measured by Swept Source OCT.Biomedicines · 2022Article
- Peripapillary RNFL/vessel density ratio in patients with type2 diabetes without clinical diabetic retinopathy.Scientific reports · 2022Article
- Comparison of Each Retinal Layer Thicknesses between Eyes with Central Retinal Vein Occlusion and Normal Contralateral Eyes.Korean journal of ophthalmology : KJO · 2022Article
- The Ganglion Cell-Inner Plexiform Layer Thickness/Vessel Density of Superficial Vascular Plexus Ratio According to the Progression of Diabetic Retinopathy.Investigative ophthalmology & visual science · 2022Article
- Comparison of retinal layer thickness and microvasculature changes in patients with diabetic retinopathy treated with intravitreous bevacizumab vs panretinal photocoagulation.Scientific reports · 2022Article
- Compensatory contribution of retinal larger vessels to perfusion density in diabetics without retinopathy.Scientific reports · 2022Article
- The impairment of the deep vascular complex in prolonged type 2 diabetes patients without clinical diabetic retinopathy.PloS one · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the effects of prolonged type 2 diabetes (T2DM) on macular microcirculation and the inner retinal layer in diabetic eyes without clinical diabetic retinopathy (DR).
methods97, 92, and 57 eyes in the control, patients with T2DM < 10 years (DM group one), and patients with T2DM ≥ 10 years (DM group two) were enrolled. The ganglion cell-inner plexiform layer (GC-IPL) thickness and superficial vessel density (VD) were compared. Linear regression analyses were performed to identify factors associated with VD in T2DM patients.
resultsGC-IPL thicknesses in the control, DM group one, and DM group two were 84.58 ± 0.89, 83.49 ± 0.70, and 79.04 ± 0.96 μm, respectively (
conclusionsWe confirmed GC-IPL thinning and decreased superficial VD in the macular areas using OCTA in T2DM patients. Patients with T2DM ≥ 10 years exhibited significantly more severe macular microcirculation impairment compared to patients with T2DM < 10 years and normal controls.
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