Evidence map›Paper›PMID 32545793›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Rifabutin Use in

James B Doub, Emily L Heil, Afua Ntem-Mensah, Renaldo Neeley, Patrick R Ching

Open access · goldAbstract readCase Reports
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Effective use of a two-dose regimen of dalbavancin to treat prosthetic joint infections and spinal hardware infections.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Trial
  3. Article
  4. Combination Antibiotic Therapy for Orthopedic Infections.Antibiotics (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. UsingFrontiers in pharmacology · 2022
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

James B DoubDivision of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Emily L HeilDepartment of Pharmacy Practice and Science, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.ORCID 0000-0002-6644-6684
Afua Ntem-MensahDepartment of Infectious Disease, Faith Regional Health Services, Norfolk, NE 68701, USA.
Renaldo NeeleyDivision of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Patrick R ChingDepartment of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, MD 21201, USA.ORCID 0000-0001-6106-2799
University of Maryland, Baltimore · USFaith Regional Health Services · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy. In these cases, rifampin was contraindicated secondary to drug-drug interactions with the patients' chronic medications. Rifabutin therapy was well tolerated with no side effects. As well, no patients had recurrence of their staphylococcal infections. This case series shows that rifabutin can be a beneficial adjuvant therapy in

Indexed as

biofilmsdrug interactionsperiprosthetic joint infectionrifabutinStaphylococcus

Identifiers

PMID32545793
PMCPMC7345564
OpenAlexW3035174640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.