Evidence map›Paper›PMID 32545608›Full record

ArticleInternational journal of molecular sciences2020

Impaired Expression of Chloroplast HSP90C Chaperone Activates Plant Defense Responses with a Possible Link to a Disease-Symptom-Like Phenotype.

Shaikhul Islam, Sachin Ashok Bhor, Keisuke Tanaka, Hikaru Sakamoto, Takashi Yaeno, Hidetaka Kaya, Kappei Kobayashi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Cloning of an Albino Mutation ofInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Novel Genomic Regions Linked toFrontiers in plant science · 2022
    Article
  6. Article
  7. Correction: Islam, S.,International journal of molecular sciences · 2020
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shaikhul IslamThe United Graduate School of Agricultural Sciences, Ehime University, Matsuyama, Ehime 790-8566, Japan.
Sachin Ashok BhorThe United Graduate School of Agricultural Sciences, Ehime University, Matsuyama, Ehime 790-8566, Japan.ORCID 0000-0003-1729-997X
Keisuke TanakaNODAI Genome Research Center, Tokyo University of Agriculture, Setagaya, Tokyo 156-8502, Japan.
Hikaru SakamotoFaculty of Bio-Industry, Tokyo University of Agriculture, Abashiri, Hokkaido 099-2493, Japan.
Takashi YaenoThe United Graduate School of Agricultural Sciences, Ehime University, Matsuyama, Ehime 790-8566, Japan.
Hidetaka KayaThe United Graduate School of Agricultural Sciences, Ehime University, Matsuyama, Ehime 790-8566, Japan.
Kappei KobayashiThe United Graduate School of Agricultural Sciences, Ehime University, Matsuyama, Ehime 790-8566, Japan.
Ehime University · JPTokyo University of Agriculture · JP

Funding

Japan Society for the Promotion of Science 26292026; 15K14664; 19K06055
6 · The paper itself

Abstract

RNA-seq analysis of a transgenic tobacco plant, i-hpHSP90C, in which chloroplast HSP90C genes can be silenced in an artificially inducible manner resulting in the development of chlorosis, revealed the up- and downregulation of 2746 and 3490 genes, respectively. Gene ontology analysis of these differentially expressed genes indicated the upregulation of ROS-responsive genes; the activation of the innate immunity and cell death pathways; and the downregulation of genes involved in photosynthesis, plastid organization, and cell cycle. Cell death was confirmed by trypan blue staining and electrolyte leakage assay, and the H

Indexed as

Gene Regulatory NetworksChloroplastsDown-RegulationGene Expression ProfilingGene Expression Regulation, PlantGene OntologyGene SilencingHSP90 Heat-Shock ProteinsHydrogen PeroxideNicotianaPhotosynthesisPlant Necrosis and ChlorosisPlant ProteinsPlants, Genetically ModifiedSequence Analysis, RNAHSP90 Heat-Shock ProteinsHydrogen PeroxidePlant Proteinscell deathchlorosisHSP90Cimmune responseRNA-seqtobaccotranscriptome

Identifiers

PMID32545608
PMCPMC7352560
OpenAlexW3035091616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.