ReviewNutrients2020
The Central Role of Iron in Human Nutrition: From Folk to Contemporary Medicine.
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 67 citations in OpenAlex.
- Discrepancies Between Predicted and Measured Microelements and Toxic Elements in Beetroot Supplemented Diets.Toxics · 2026Article
- From Iron Deficiency to Overload: A Missing Link in the Mechanisms of Cardiac Autonomic Nervous System Dysfunction.Journal of clinical medicine · 2026Review
- Heme and CO metabolism by the canonical human heme oxygenases.Journal of inorganic biochemistry · 2026Review
- Agronomic biofortification in crops with Zn: the zinc-iron interaction dilemma.Frontiers in plant science · 2026Review
- Iron bioremediation by utilizing biochar-bacterial composites.BMC microbiology · 2025Article
- Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy.Frontiers in nutrition · 2025Review
- The Interplay Between Vitamin D Deficiency, Iron Status, and Anemia Risk in Moroccan Women of Reproductive Age: A Cross-Sectional Analysis.Epidemiologia (Basel, Switzerland) · 2024Article
- Construction of novel π-bridged fluorescent probes for FeAnalytical and bioanalytical chemistry · 2024Article
- Historical shifting in grain mineral density of landmark rice and wheat cultivars released over the past 50 years in India.Scientific reports · 2023Article
- Review
- The Chelating Ability of Plant Polyphenols Can Affect Iron Homeostasis and Gut Microbiota.Antioxidants (Basel, Switzerland) · 2023Review
- Oral manifestations of iron imbalance.Frontiers in nutrition · 2023Article
- Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study.Life (Basel, Switzerland) · 2022Article
- Nutrition Disturbances and Metabolic Complications in Kidney Transplant Recipients: Etiology, Methods of Assessment and Prevention-A Review.Nutrients · 2022Review
- Vascular Aging and Damage in Patients with Iron Metabolism Disorders.Diagnostics (Basel, Switzerland) · 2022Review
- Iron- and Neuromelanin-Weighted Neuroimaging to Study Mitochondrial Dysfunction in Patients with Parkinson's Disease.International journal of molecular sciences · 2022Review
- Dietary Approaches to Iron Deficiency Prevention in Childhood-A Critical Public Health Issue.Nutrients · 2022Review
- Integration of the Metabolomic and Transcriptome Analysis Reveals the Remarkable Compounds ofInternational journal of molecular sciences · 2022Article
- Prediction of Long-Term Recovery From Disability Using Hemoglobin-Based Models: Results From a Cohort of 1,392 Patients Undergoing Spine Surgery.Frontiers in surgery · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is a fundamental element in human history, from the dawn of civilization to contemporary days. The ancients used the metal to shape tools, to forge weapons, and even as a dietary supplement. This last indication has been handed down until today, when martial therapy is considered fundamental to correct deficiency states of anemia. The improvement of the martial status is mainly targeted with dietary supplements that often couple diverse co-factors, but other methods are available, such as parenteral preparations, dietary interventions, or real-world approaches. The oral absorption of this metal occurs in the duodenum and is highly dependent upon its oxidation state, with many absorption influencers possibly interfering with the intestinal uptake. Bone marrow and spleen represent the initial and ultimate step of iron metabolism, respectively, and the most part of body iron circulates bound to specific proteins and mainly serves to synthesize hemoglobin for new red blood cells. Whatever the martial status is, today's knowledge about iron biochemistry allows us to embrace exceedingly personalized interventions, which however owe their success to the mythical and historical events that always accompanied this metal.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.