ArticleCancers2020
Should the Number of Metastatic Pelvic Lymph Nodes be Integrated into the 2018 Figo Staging Classification of Early Stage Cervical Cancer?
Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05421650 (Therapeutic Effect of Surgical Debulking of Metastatic Lymph Nodes in Cervical Cancer Stage IIICr), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Therapeutic Effect of Surgical Debulking of Metastatic Lymph Nodes in Cervical Cancer Stage IIICr: A Phase III, Randomized Controlled Clinical Trial
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Survival outcomes in IIIC cervical cancer by treatment strategies: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- A Hybrid Model-Based Clinicopathological Features and Radiomics Based on Conventional MRI for Predicting Lymph Node Metastasis and DFS in Cervical Cancer.Journal of imaging informatics in medicine · 2026Article
- Article
- Rationality of FIGO 2018 IIIC cervical cancer according to local tumor and pelvic lymph node metastatic extent-a cohort study.BMC women's health · 2025Article
- Construction and evaluation of a prognostic model for cervical cancer based on dynamic hematological and clinical features.BMC cancer · 2025Article
- Age and socioeconomic disparities in cervical cancer incidence and mortality: a SEER-based analysis.Frontiers in public health · 2025Article
- Therapeutic effects of surgical debulking of metastatic lymph nodes in cervical cancer IIICr: a trial protocol for a phase III, multicenter, randomized controlled study (KGOG1047/DEBULK trial).Journal of gynecologic oncology · 2024Article
- Article
- Stage migration and survival outcomes in patients with cervical cancer at Stage IIIC according to the 2018 FIGO staging system: a systematic review and meta-analysis.Frontiers in oncology · 2024Review
- Initial treatment for FIGO 2018 stage IIIC cervical cancer based on histological type: A 14-year multicenter study.Cancer medicine · 2023Article
- Surgically treated cervical cancer in a high-risk group in the era of the 2018 FIGO staging schema: a nationwide study.Scientific reports · 2023Article
- Validation of the 2018 FIGO Staging System for Predicting the Prognosis of Patients With Stage IIIC Cervical Cancer.Clinical Medicine Insights. Oncology · 2023Article
- Comparative single-center study between modified laparoscopic radical hysterectomy and open radical hysterectomy for early-stage cervical cancer.World journal of surgical oncology · 2022Article
- The prognostic value of the number of positive lymph nodes and the lymph node ratio in early-stage cervical cancer.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more accurate than FIGO 2009.The Journal of international medical research · 2022Article
- Effect of Number of Retrieved Lymph Nodes on Prognosis in FIGO Stage IA1-IIA2 Cervical Cancer Patients Treated With Primary Radical Surgery.Clinical Medicine Insights. Oncology · 2022Article
- Development and Validation of Novel Nomograms to Predict the Overall Survival and Cancer-Specific Survival of Cervical Cancer Patients With Lymph Node Metastasis.Frontiers in oncology · 2022Article
- Radiomic models for lymph node metastasis prediction in cervical cancer: can we think beyond sentinel lymph node?Translational oncology · 2021Article
- Impact of surgeon learning curve in minimally invasive radical hysterectomy on early stage cervical cancer patient survival.Facts, views & vision in ObGyn · 2021Article
- The Combination of T Stage and the Number of Pathologic Lymph Nodes Provides Better Prognostic Discrimination in Early-Stage Cervical Cancer With Lymph Node Involvement.Frontiers in oncology · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLymph node status has become part of the new staging system for cervical cancer (CC). It has been shown that patients staged as IIIC1 had heterogeneous prognoses and, in some cases, experienced better outcomes than patients with lower stages. We evaluated the impact of the number of metastatic pelvic lymph nodes (MPLNs) among patients with stage IIIC1 cervical cancer.
methodsSurvival analyses were conducted in order to identify the best cut-off prognostic value relative to the number of MPLNs. Disease free survival (DFS) was considered the main outcome.
results541 patients were included in the study. Eighty-nine patients were of stage IIIC1. The best prognostic cut-off value of the number of MPLNs was 2. Patients with >2 MPLNs ( DISCUSSION: Using a cut-off value of 2, the number of MPLNs could better predict prognostic outcomes within stage IIIC1 cervical cancer and have potential implications for therapeutic decision-making in the treatment of patients with stage IIIC1 CC.
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