Evidence map›Paper›PMID 32545475›Full record

ArticleToxins2020

Involvement of the Endothelin Receptor Type A in the Cardiovascular Inflammatory Response Following Scorpion Envenomation.

Amina Sifi, Sonia Adi-Bessalem, Fatima Laraba-Djebari

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Proteasome-driven modulation of immune and oxidative pathways during scorpion envenomation pathogenesis.The journal of venomous animals and toxins including tropical diseases · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amina SifiUSTHB, Faculty of Biological Sciences, Laboratory of Cellular and Molecular Biology; BP 32 El-Alia, Bab Ezzouar 16111, Algiers, Algeria.
Sonia Adi-BessalemUSTHB, Faculty of Biological Sciences, Laboratory of Cellular and Molecular Biology; BP 32 El-Alia, Bab Ezzouar 16111, Algiers, Algeria.
Fatima Laraba-DjebariUSTHB, Faculty of Biological Sciences, Laboratory of Cellular and Molecular Biology; BP 32 El-Alia, Bab Ezzouar 16111, Algiers, Algeria.ORCID 0000-0003-4641-261X
University of Sciences and Technology Houari Boumediene · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated levels of endothelin-1 (ET-1) were recorded in sera of scorpion sting patients. However, no studies focused on the mechanism of ET-1 involvement in the pathogenesis of scorpion envenomation, particularly in the cardiovascular system which is seriously affected in severe cases of scorpion stings. Inflammation induced by

Indexed as

AnimalsAnti-Inflammatory AgentsCardiovascular DiseasesCardiovascular SystemDisease Models, AnimalEndothelin-1Endothelin A Receptor AntagonistsInflammationInflammation MediatorsMaleMicePeptides, CyclicReceptor, Endothelin AScorpion StingsScorpion VenomsSignal TransductionAnti-Inflammatory Agentscyclo(Trp-Asp-Pro-Val-Leu)Endothelin-1Endothelin A Receptor AntagonistsInflammation MediatorsPeptides, CyclicReceptor, Endothelin AScorpion Venomscardiovascular systemendothelin-1ETA-Rinflammationmatrix metalloproteinases (MMP-2 and MMP-9)oxidative stressscorpion envenomation

Identifiers

PMID32545475
PMCPMC7374423
OpenAlexW3034616973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.