SynthesisInternational journal of environmental research and public health2020
Effects of COVID-19 Infection during Pregnancy and Neonatal Prognosis: What Is the Evidence?
Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 8 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Consequences and implications of the coronavirus disease (COVID-19) on pregnancy and newborns: A comprehensive systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Pooled it
- Pooled it
- Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews.International journal of environmental research and public health · 2021Pooled it
- COVID-19 and pregnancy: An umbrella review of clinical presentation, vertical transmission, and maternal and perinatal outcomes.PloS one · 2021Pooled it
- Problems with Early Systematic Reviews: The Case of Coronavirus Disease 2019 (COVID-19) in Pregnancy.Maternal and child health journal · 2021Pooled it
- Clinical Characteristics and Neonatal Outcomes of Pregnant Patients With COVID-19: A Systematic Review.Frontiers in medicine · 2020Pooled it
- COVID-19 in pregnancy: the foetal perspective-a systematic review.BMJ paediatrics open · 2020Pooled it
- Guideline
- Retrospective Cohort Study of Pregnancy Maternal Outcomes of Women With COVID-19 in King Salman Armed Forces Hospital, Tabuk, Kingdom of Saudi Arabia.Obstetrics and gynecology international · 2025Article
- Perinatal Outcomes during versus Prior to the COVID-19 Pandemic and the Role of Maternal Depression and Perceived Stress: A Report from the ECHO Program.American journal of perinatology · 2024Article
- The clinical manifestations and pregnancy outcomes of COVID-19 infection at a tertiary care hospital.Pakistan journal of medical sciences · 2024Article
- Maternal Characteristics and Outcomes Affected by COVID-19 Pandemic in Indonesia.Journal of obstetrics and gynaecology of India · 2023Article
- A Case Report of Bowel Perforation in a Gravid COVID-19 Patient.Case reports in medicine · 2023Article
- Review
- First Neonates with Vertical Transmission of SARS-CoV-2 Infection in Late Pregnancy in West Part of Romania: Case Series.Diagnostics (Basel, Switzerland) · 2022Article
- COVID-19 and tuberculosis co-infection in pregnancy - A case series and review.Journal of mother and child · 2022Article
- Clinical manifestations and pregnancy outcomes of COVID-19 in indonesian referral hospital in central pandemic area.Obstetrics & gynecology science · 2022Article
- Management and short-term outcomes of neonates born to mothers with active perinatal SARS-CoV-2 infection.BMC pediatrics · 2021Article
- Hearing screening outcomes in neonates of SARS-CoV-2 positive pregnant women.International journal of pediatric otorhinolaryngology · 2021Article
- Maternal and perinatal outcomes related to COVID-19 and pregnancy: An overview of systematic reviews.Acta obstetricia et gynecologica Scandinavica · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThis study's aims are to assess the current evidence presented in the literature regarding the potential risks of COVID-19 infection among pregnant women and consequent fetal transmission.
methodsa systematic literature review assessing papers published in the most comprehensive databases in the field of health intended to answer the question, "What are the effects of COVID-19 infection during pregnancy, and what is the neonatal prognosis?"
results49 papers published in 2020 were eligible, presenting low levels of evidence. A total of 755 pregnant women and 598 infants were assessed; more than half of pregnant women had C-sections (379/65%). Only 493 (82%) infants were tested for SARS-CoV-2, nine (2%) of whom tested positive. There is, however, no evidence of vertical transmission based on what has been assessed so far, considering there are knowledge gaps concerning the care provided during and after delivery, as well as a lack of suitable biological samples for testing SARS-CoV-2.
conclusionsWe cannot rule out potential worsening of the clinical conditions of pregnant women infected with SARS-CoV-2, whether the infection is associated with comorbidities or not, due to the occurrence of respiratory disorders, cardiac rhythm disturbances, and acid-base imbalance, among others. We recommend relentless monitoring of all pregnant women in addition to testing them before delivery or the first contact with newborns.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.