Evidence map›Paper›PMID 32545250›Full record

Trial reportNutrients2020

In "High-Risk" Infants with Sufficient Vitamin D Status at Birth, Infant Vitamin D Supplementation Had No Effect on Allergy Outcomes: A Randomized Controlled Trial.

Kristina Rueter, Anderson P Jones, Aris Siafarikas, Ee-Mun Lim, Susan L Prescott, Debra J Palmer

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Effect of Oral Vitamin D3 Supplementation in Exclusively Breastfed Newborns: Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Trial
  6. Review
  7. Review
  8. Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. The Influence of Sunlight Exposure and Sun Protecting Behaviours on Allergic Outcomes in Early Childhood.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kristina RueterSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
Anderson P JonesTelethon Kids Institute, University of Western Australia, 15 Hospital Avenue, Nedlands, WA 6009, Australia.
Aris SiafarikasSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0002-9963-3988
Ee-Mun LimDepartment of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.
Susan L PrescottSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0003-4845-8590
Debra J PalmerSchool of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.ORCID 0000-0003-2498-8343
The Kids Research Institute Australia · AUSir Charles Gairdner Hospital · AUThe University of Western Australia · AU

Funding

Asthma Foundation of Western Australia 2013National Health and Medical Research Council APP1144544Princess Margaret Hospital Foundation 2014Telethon-New Children's Hospital Research Fund 2012 (Round 1)
6 · The paper itself

Abstract

Lower vitamin D status at birth and during infancy has been associated with increased incidence of eczema and food allergies. The aim of this study was to investigate the effect of early infancy vitamin D supplementation on allergic disease outcomes in infants at "hereditary risk" of allergic disease, but who had sufficient vitamin D levels at birth. Here, we report the early childhood follow-up to 2.5 years of age of "high-risk" infants who participated in a double-blinded, randomized controlled trial. For inclusion in this trial, late gestation (36-40 weeks) maternal 25-hydroxyvitamin D levels needed to be ≥50 nmol/L. Infants were randomized to either oral vitamin D supplementation of 400 IU/day (

Indexed as

Dietary SupplementsNegative ResultsNutritional StatusDouble-Blind MethodEczemaFemaleFollow-Up StudiesFood HypersensitivityHumansInfantInfant, NewbornMaleRiskVitamin D25-hydroxyvitamin DVitamin Dallergen sensitizationallergic diseaseeczemahereditary riskinfantpreventionrandomized controlled trialvitamin Dwheeze

Identifiers

PMID32545250
PMCPMC7353265
OpenAlexW3035191790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.