Evidence map›Paper›PMID 32545166›Full record

ArticleNutrients2020

Faster Short-Chain Fatty Acid Absorption from the Cecum Following Polydextrose Ingestion Increases the Salivary Immunoglobulin A Flow Rate in Rats.

Yuko Yamamoto, Toshiya Morozumi, Toru Takahashi, Juri Saruta, Masahiro To, Wakako Sakaguchi, Tomoko Shimizu, Nobuhisa Kubota, Keiichi Tsukinoki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Re-evaluation of polydextrose (E 1200) as a food additive.EFSA journal. European Food Safety Authority · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuko YamamotoDepartment of Junior College, School of Dental Hygiene, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.
Toshiya MorozumiDivision of Periodontology, Department of Oral Interdisciplinary Medicine, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.ORCID 0000-0002-7151-1292
Toru TakahashiDepartment of Health and Nutrition, Faculty of Human Health, Kanazawa Gakuin University, 10 Sue-machi, Kanazawa 9201392, Ishikawa, Japan.ORCID 0000-0003-2665-3520
Juri SarutaDivision of Environmental Pathology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.ORCID 0000-0002-7566-3330
Masahiro ToDivision of Dental Anatomy, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.
Wakako SakaguchiDivision of Environmental Pathology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.
Tomoko ShimizuDepartment of Highly Advanced Stomatology, Graduate School of Dentistry, Kanagawa Dental University, 3-31-6 Tsuruya, Kanagawa-ku, Yokohama 2210835, Kanagawa, Japan.
Nobuhisa KubotaDivision of Environmental Pathology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.
Keiichi TsukinokiDivision of Environmental Pathology, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka, Yokosuka 2388580, Kanagawa, Japan.
Kanagawa Dental University · JPKanazawa Gakuin University · JP

Funding

JSPS KAKENHI 15H06809, 17K11694
6 · The paper itself

Abstract

Salivary immunoglobulin A (IgA) plays a vital role in preventing upper respiratory tract infections (URTI). In our previous study, we showed that the intake of carbohydrates increases the intestinal levels of short-chain fatty acids (SCFAs), which in turn increase salivary IgA levels. However, the mechanism underlying this phenomenon has not been fully elucidated. In this study, we investigated in rats the effect of polydextrose (PDX) ingestion on salivary IgA level and SCFA concentration in cecal digesta and the portal vein. Five-week-old rats were fed with a fiber-free diet (control) or with 40 g/kg of PDX for 28 days. Compared to the control, ingestion of PDX led to a higher salivary IgA flow rate (

Indexed as

Intestinal AbsorptionAnimalsCecumEatingFatty Acids, VolatileFermentationGene ExpressionGlucansImmunoglobulin AMalePortal VeinRats, WistarReceptors, Cell SurfaceSalivaSalivary GlandsFatty Acids, VolatileGlucansImmunoglobulin AOSCAR protein, humanpolydextroseReceptors, Cell SurfaceIgApolydextrosepolymeric immunoglobulin receptorratssalivashort-chain fatty acids

Identifiers

PMID32545166
PMCPMC7353249
OpenAlexW3034368928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.