Evidence map›Paper›PMID 32544911›Full record

ReviewInternational archives of allergy and immunology2020

Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection.

Hans-Uwe Simon, Alexander V Karaulov, Martin F Bachmann

Open access · hybridAbstract readReview
In one paragraph

Review in International archives of allergy and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Hans-Uwe SimonInstitute of Pharmacology, University of Bern, Bern, Switzerland, hus@pki.unibe.ch.
Alexander V KaraulovDepartment of Clinical Immunology and Allergology, Sechenov University, Moscow, Russian Federation.
Martin F BachmannDepartment of Rheumatology, Immunology and Allergology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
University of Bern · CHSechenov University · RU

Funding

Swiss National Science Foundation
6 · The paper itself

Abstract

A vaccine to protect against COVID-19 is urgently needed. Such a vaccine should efficiently induce high-affinity neutralizing antibodies which neutralize SARS-CoV-2, the cause of COVID-19. However, there is a concern regarding both vaccine-induced eosinophilic lung disease and eosinophil-associated Th2 immunopotentiation following infection after vaccination. Here, we review the anticipated characteristics of a COVID-19 vaccine to avoid vaccine-associated eosinophil immunopathology.

Indexed as

Antibodies, NeutralizingBetacoronavirusCoronavirus InfectionsCOVID-19COVID-19 VaccinesEosinophilsHumansPandemicsPneumonia, ViralSARS-CoV-2Th2 CellsVaccinationViral VaccinesAntibodies, NeutralizingCOVID-19 VaccinesViral VaccinesCOVID-19EosinophilImmunityImmunopathologySARS-CoV-2Vaccination

Identifiers

PMID32544911
PMCPMC7360494
OpenAlexW3035013678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.