ArticleJournal of medical virology2020
Dysregulation of the immune response affects the outcome of critical COVID-19 patients.
Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Article
- Post-Pandemic Surge in Complications of Acute Otitis Media.Turkish archives of otorhinolaryngology · 2025Article
- The role of immune activation and antigen persistence in acute and long COVID.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023Review
- Immune responses in mildly versus critically ill COVID-19 patients.Frontiers in immunology · 2023Review
- Immunophenotyping characteristics and outcome of COVID-19 patients: peripheral blood CD8+T cell as a prognostic biomarker for patients with Nirmatrelvir.Frontiers in immunology · 2023Article
- Lung T cell response in COVID-19.Frontiers in immunology · 2023Review
- Cellular immune states in SARS-CoV-2-induced disease.Frontiers in immunology · 2022Review
- The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.Frontiers in immunology · 2022Article
- The role of TNFR2Life sciences · 2021Review
- FANSY POSTCOV: A composite clinical immunological predictive index for post-COVID-19 syndrome unveils distinctive features in a cohort study of mild to critical patients.Clinical and translational medicine · 2021Article
- Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity.Cell reports · 2021Article
- Imbalanced Immune Response of T-Cell and B-Cell Subsets in Patients with Moderate and Severe COVID-19.Viruses · 2021Article
- Profound dysregulation of T cell homeostasis and function in patients with severe COVID-19.Allergy · 2021Article
- Immunological Aspects of SARS-CoV-2 Infection and the Putative Beneficial Role of Vitamin-D.International journal of molecular sciences · 2021Review
- Contribution of STAT3 to the pathogenesis of COVID-19.Microbial pathogenesis · 2021Review
- Dysregulation of the immune response in coronavirus disease 2019.Cell biology international · 2021Review
- COVID-19 illness and autoimmune diseases: recent insights.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021Review
- T cell phenotypes in COVID-19 - a living review.Oxford open immunology · 2021Article
- Immune Signature Linked to COVID-19 Severity: A SARS-Score for Personalized Medicine.Frontiers in immunology · 2021Article
- The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells.Frontiers in microbiology · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Critical cases of coronavirus disease 2019 (COVID-19) are associated with a high risk of mortality. It remains unclear why patients with the same critical condition have different outcomes. We aimed to explore relevant factors that may affect the prognosis of critical COVID-19 patients. Six critical COVID-19 inpatients were included in our study. The six patients were divided into two groups based on whether they had a good or poor prognosis. We collected peripheral blood samples at admission and the time point of exacerbation to compare differences in the phenotypes and functions of major populations of immune cells between the groups. On admission, compared to patients with poor prognoses, those with good prognoses had significantly higher counts of monocytes (P < .05), macrophages (P < .05), higher frequency of CD3
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