Evidence map›Paper›PMID 32543351›Full record

ReviewOpen biology2020

Role of antioxidants and a nutrient rich diet in Alzheimer's disease.

Gerald Veurink, George Perry, Sandeep Kumar Singh

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Open biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  12. Editorial: Nutrition for an aging brain.Frontiers in nutrition · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Gerald VeurinkNaturels, Armadale, Western Australia, Australia.
George PerryDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX, USA.
Sandeep Kumar SinghIndian Scientific Education and Technology Foundation, Lucknow 226002, India.
The University of Texas at San Antonio · USThe University of Western Australia · AUUnited States India Educational Foundation · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The joint attack on the body by metabolic acidosis and oxidative stress suggests that treatment in degenerative diseases, including Alzheimer's disease (AD), may require a normalizing of extracellular and intracellular pH with simultaneous supplementation of an antioxidant combination cocktail at a sufficiently high dose. Evidence is also accumulating that combinations of antioxidants may be more effective, taking advantage of synergistic effects of appropriate antioxidants as well as a nutrient-rich diet to prevent and reverse AD. This review focuses on nutritional, nutraceutical and antioxidant treatments of AD, although they can also be used in other chronic degenerative and neurodegenerative diseases.

Indexed as

Alzheimer DiseaseAntioxidantsDietDietary SupplementsDrug SynergismHumansOxidative StressAntioxidantsAlzheimer's diseaseantioxidantneuroprotectionnutraceuticalnutrientoxidative stress

Identifiers

PMID32543351
PMCPMC7333894
OpenAlexW3035541122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.