Evidence map›Paper›PMID 32543182›Full record

ArticleBiochemistry2020

Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences.

Shi-Qing Mao, Sergio Martínez Cuesta, David Tannahill, Shankar Balasubramanian

Open access · hybridAbstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

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  14. DNA Methylation in the Adaptive Response to Exercise.Sports medicine (Auckland, N.Z.) · 2024
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Enzymology of Mammalian DNA Methyltransferases.Advances in experimental medicine and biology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shi-Qing MaoCancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge CB2 0RE, U.K.
Sergio Martínez CuestaCancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge CB2 0RE, U.K.
David TannahillCancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge CB2 0RE, U.K.
Shankar BalasubramanianCancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge CB2 0RE, U.K.ORCID 0000-0002-0281-5815
Cancer Research UK · GBUniversity of Cambridge · GB

Funding

Cancer Research UK 19836Cancer Research UK C14303/A17197Wellcome Trust 209441/Z/17/Z
6 · The paper itself

Abstract

Cytosine methylation is an important epigenetic mark, but how the distinctive patterns of DNA methylation arise remains elusive. For the first time, we systematically investigated how these patterns can be imparted by the inherent enzymatic preferences of mammalian

Indexed as

DNA MethylationAnimalsCpG IslandsDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNA Methyltransferase 3BEmbryonic Stem CellsGenomeHumansNucleotide MotifsSubstrate SpecificityDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3ADNA Methyltransferase 3BDNMT3A protein, humanDnmt3a protein, mouse

Identifiers

PMID32543182
PMCPMC7364778
OpenAlexW3034575908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.