Evidence map›Paper›PMID 32542914›Full record

ArticlePediatric transplantation2020

Varying presentations of COVID-19 in young heart transplant recipients: A case series.

Hannah Lee, Benjamin S Mantell, Marc E Richmond, Sabrina P Law, Warren A Zuckerman, Linda J Addonizio, Teresa M Lee, Irene D Lytrivi

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Pediatric transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Pediatric transplantation during the COVID-19 pandemic.World journal of transplantation · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cardiac Manifestations in COVID-19 Patients: A Focus on the Pediatric Population.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Review
  13. Article
  14. Article
  15. Coronavirus disease 2019 (COVID-19) in the heart transplant population: a single-centre experience.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2020
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hannah LeeDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Benjamin S MantellDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Marc E RichmondDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0001-5491-8085
Sabrina P LawDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Warren A ZuckermanDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0003-3856-7726
Linda J AddonizioDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Teresa M LeeDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.
Irene D LytriviDepartment of Pediatrics, Program for Pediatric Cardiomyopathy, Heart Failure and Transplantation, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0002-9688-0879
Columbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunosuppression is considered a risk factor for more severe clinical presentation of COVID-19. Limited data regarding clinical outcome exist in adults, whereas very little is known about the spectrum of the disease in pediatric heart transplant recipients.

methodsWe retrospectively reviewed the charts of young heart transplant patients from our tertiary care center during the coronavirus pandemic in New York City and identified patients infected with SARS-CoV-2.

resultsWe present four cases with COVID-19 disease and elaborate on their presentation and clinical course.

conclusionsAlthough far from conclusive and limited by the small sample size and selection bias, these cases demonstrate mild and self-limited disease despite immunosuppressive therapy and various comorbidities that are expected to increase the severity of the clinical picture based on extrapolation from the adult experience with this novel disease.

Indexed as

Heart TransplantationAdolescentAdultChild, PreschoolCOVID-19COVID-19 TestingDiagnosis, DifferentialFemaleHumansImmunosuppressive AgentsInfantMaleRetrospective StudiesSARS-CoV-2Transplant RecipientsImmunosuppressive AgentsCOVID-19heart transplantationimmunosuppressionpediatrics

Identifiers

PMID32542914
PMCPMC7323105
OpenAlexW3034637972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.