Evidence map›Paper›PMID 32542735›Full record

ReviewJournal of cellular physiology2021

An updated review of the association of host genetic factors with susceptibility and resistance to COVID-19.

Somayeh Mohammadpour, Amir Torshizi Esfahani, Mehrdad Halaji, Mina Lak, Reza Ranjbar

Abstract readReview
In one paragraph

Review in Journal of cellular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Observational
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  17. Human genetic basis of coronavirus disease 2019.Signal transduction and targeted therapy · 2021
    Review
  18. ACE I/D polymorphism in Czech first-wave SARS-CoV-2-positive survivors.Clinica chimica acta; international journal of clinical chemistry · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Somayeh MohammadpourDepartment of Biology, Islamic Azad University, Marvdasht Branch, Marvdasht, Iran.ORCID 0000-0001-6492-1691
Amir Torshizi EsfahaniDepartment of Biology, Faculty of Biological Sciences, Islamic Azad University, North Tehran Branch, Tehran, Iran.ORCID 0000-0002-8965-5753
Mehrdad HalajiDepartment of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0002-8965-5753
Mina LakDepartment of Microbiology, Faculty of Advanced Science and Technology, Islamic Azad University Tehran Medical Sciences, Tehran, Iran.
Reza RanjbarMolecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-8593-1514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human populations sparked a global pandemic of the coronavirus disease 2019 (COVID-19). According to preliminary data, about 14% of cases are considered severe and 5% of cases result in critical illness and, reported case fatality rates vary from 1% to more than 7%. However, the symptoms of the disease and the clinical outcome are very different in infected people. In view of these differences, it is clearly apparent that to gain insight into the biology of the SARS-CoV-2, it is important to study not just the infectious particle in itself but also to investigate the virus-host cell interactions that occur during infection. This review seeks to consider the various aspects of genetic factors in determining the susceptibility and host resistance to SARS-CoV-2 throughout the recently published literature.

Indexed as

Genetic Predisposition to DiseaseCommunicable Diseases, EmergingCOVID-19Genome, ViralHumansSARS-CoV-2COVID-19geneticsresistanceSARS-CoV-2susceptibility

Identifiers

PMID32542735
PMCPMC7323230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.