ArticleGinekologia polska2020
Uterine leiomyomas: correlation between histologic composition and stiffness via magnetic resonance elastography - a Pilot Study.
Article in Ginekologia polska, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Magnetic resonance elastography (MRE) for the evaluation of fibrosis in patients with benign uterine disorders: a systematic review.Abdominal radiology (New York) · 2026Pooled it
- Multi-institutional survey on abdominopelvic applications of MR elastography.European radiology · 2026Article
- Case Report: A rare case of breast leiomyoma with literature review.Frontiers in oncology · 2026Article
- High-frequency shear wave MR elastography of parotid glands: custom driver design and preliminary results.Scientific reports · 2024Article
- 3D vector MR elastography applications in small organs.Magnetic resonance imaging · 2024Review
- Multiparametric quantitative magnetic resonance imaging of uterine fibroids for prediction of growth rate-a pilot study.Quantitative imaging in medicine and surgery · 2024Article
- Postprandial splenic stiffness changes on magnetic resonance elastography in a young healthy population.NMR in biomedicine · 2024Article
- Evaluation of Spleen Stiffness in Young Healthy Volunteers Using Magnetic Resonance Elastography.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo evaluate magnetic resonance elastography as a tool for characterizing uterine leimyomas. MATERIAL AND
methodsAt total of 12 women with symptomatic leiomyomas diagnosed in physical and ultrasound examinations were enrolled in this pilot study. Before surgery, all patients underwent magnetic resonance elastography of the uterus using a 1.5 T MR whole-body scanner (Optima, GE Healthcare, Milwaukee, WI, USA). Surgical specimens were forwarded for histological examination. The findings were allocated into 3 categories depending on the percentage content of connective tissue: below 15%, from 15 to 30% and more than 30%. The median stiffness of leiomyomas for each of the group was calculated. The U-Mann Whitney test was used for statistical analysis.
resultsThe stiffness of the leiomyomas ranged between 3.7-6.9 kPa (median value 4.9 kPa). The concentration of extracellular components in the leiomyomas did not exceed 40%. An increasing trend of the stiffness with the growing percentage of extracellular component was observed. Stiffness of the leiomyomas obtained by MRE varies depending on microscopic composition.
conclusionsThe value of stiffness shows a trend of increasing with the percentage of extracellular component of the leiomyoma. Further studies are required to assess the usefulness of MRE in diagnostics of uterine leiomyomas.
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